低剂量阿糖胞苷诱导猫淋巴细胞性白血病缓解
Low-dose cytosine arabinoside-induced remission of lymphoblastic leukemia in a cat.
作者信息
Helfand S C
机构信息
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.
出版信息
J Am Vet Med Assoc. 1987 Sep 15;191(6):707-10.
PMID:2824412
Abstract
Low-dose cytosine arabinoside (10 mg/m2, q 12 h), an antimetabolite chemotherapeutic agent, was administered subcutaneously to a cat with aleukemic lymphoblastic leukemia. After several weeks of this treatment, there was marked improvement in the neutrophil count and PCV, as well as restoration of adequate numbers of normal bone marrow cells. The remission lasted 10 weeks.
摘要
低剂量阿糖胞苷（10毫克/平方米，每12小时一次），一种抗代谢类化疗药物，被皮下注射给一只患非白血性淋巴细胞白血病的猫。经过几周的这种治疗后，中性粒细胞计数和红细胞压积有显著改善，同时正常骨髓细胞数量也恢复到足够水平。缓解持续了10周。
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