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猫急性巨核细胞白血病的阿糖胞苷化疗

Cytosine arabinoside chemotherapy for acute megakaryocytic leukemia in a cat.

作者信息

Hamilton T A, Morrison W B, DeNicola D B

机构信息

Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47905.

出版信息

J Am Vet Med Assoc. 1991 Aug 1;199(3):359-61.

PMID:1917643
Abstract

Myeloproliferative disease in a cat was characterized by severe, nonregenerative anemia, circulating blast cells, and proliferation of bizarre megakaryoblasts in the bone marrow. The number of circulating platelets was markedly higher than normal at initial examination. Chemotherapy with cytosine arabinoside was successful in inducing complete remission and maintaining survival for 122 days.

摘要

一只猫的骨髓增殖性疾病的特征为严重的非再生性贫血、循环母细胞以及骨髓中奇异巨核母细胞的增殖。初次检查时,循环血小板数量明显高于正常水平。使用阿糖胞苷进行化疗成功诱导了完全缓解,并维持生存122天。

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