肥厚性硬脑膜炎与抗利尿激素分泌不当综合征：巧合还是因果关系？
Hypertrophic Pachymeningitis and the Syndrome of Inappropriate Antidiuretic Hormone Secretion: Coincidence or Cause?
作者信息
Harsch Igor Alexander, Schiffer Anne, Konturek Peter C
机构信息
Division of Endocrinology and Metabolism, Department of Internal Medicine II, Thuringia Clinic Saalfeld, Saalfeld, Germany.
出版信息
Med Princ Pract. 2017;26(3):289-291. doi: 10.1159/000466697. Epub 2017 Feb 28.
OBJECTIVE
To investigate a potential cause of the syndrome of inappropriate antidiuretic hormone secretion (SIADH).
CLINICAL PRESENTATION AND INTERVENTION
A 70-year-old female patient had nausea and collapsed. Although euvolemic, pathological laboratory findings showed hyponatremia and hypoosmolality, and cerebral magnetic resonance imaging showed hypertrophic pachymeningitis. Secondary hypertrophic pachymeningitis was excluded. Other nonneurological reasons for SIADH were also excluded. Moderate fluid restriction restored an almost normal serum osmolality and sodium.
CONCLUSION
This case of SIADH was conservatively treated with moderate fluid restriction that almost restored normal serum osmolality and sodium levels.
目的
探讨抗利尿激素分泌异常综合征（SIADH）的潜在病因。
临床表现与干预措施
一名70岁女性患者出现恶心并晕倒。尽管血容量正常，但实验室检查结果显示低钠血症和低渗血症，脑部磁共振成像显示肥厚性硬脑膜炎。排除了继发性肥厚性硬脑膜炎。其他导致SIADH的非神经学原因也被排除。适度限制液体摄入使血清渗透压和钠水平几乎恢复正常。
结论
该例SIADH患者通过适度限制液体摄入进行保守治疗，血清渗透压和钠水平几乎恢复正常。
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