Hanak Brian W, Bonow Robert H, Harris Carolyn A, Browd Samuel R
Department of Neurological Surgery, University of Washington and Seattle Children's Hospital, Seattle, WA, USA.
Pediatr Neurosurg. 2017;52(6):381-400. doi: 10.1159/000452840. Epub 2017 Mar 2.
Although cerebrospinal fluid (CSF) shunt placement is the most common procedure performed by pediatric neurosurgeons, shunts remain among the most failure-prone life-sustaining medical devices implanted in modern medical practice. This article provides an overview of the mechanisms of CSF shunt failure for the 3 most commonly employed definitive CSF shunts in the practice of pediatric neurosurgery: ventriculoperitoneal, ventriculopleural, and ventriculoatrial. The text has been partitioned into the broad modes of shunt failure: obstruction, infection, mechanical shunt failure, overdrainage, and distal catheter site-specific failures. Clinical management strategies for the various modes of shunt failure are discussed as are research efforts directed towards reducing shunt complication rates. As it is unlikely that CSF shunting will become an obsolete procedure in the foreseeable future, it is incumbent on the pediatric neurosurgery community to maintain focused efforts to improve our understanding of and management strategies for shunt failure and shunt-related morbidity.
尽管脑脊液(CSF)分流术是儿科神经外科医生最常进行的手术,但在现代医疗实践中,分流器仍是最容易出现故障的维持生命的医疗设备之一。本文概述了儿科神经外科实践中最常用的三种确定性CSF分流器(脑室-腹腔分流术、脑室-胸腔分流术和脑室-心房分流术)发生CSF分流失败的机制。文本已分为分流失败的主要模式:梗阻、感染、机械性分流失败、过度引流和远端导管部位特异性失败。讨论了针对各种分流失败模式的临床管理策略以及旨在降低分流并发症发生率的研究工作。由于在可预见的未来,脑脊液分流术不太可能过时,儿科神经外科界有责任持续集中精力,以增进我们对分流失败及分流相关发病率的理解和管理策略。