Department of Neurological Surgery, The University of Chicago, 5841 S. Maryland Ave, Chicago, IL, 60637, USA.
Pritzker School of Medicine, University of Chicago, Chicago, IL, USA.
Neurosurg Rev. 2022 Aug;45(4):2615-2638. doi: 10.1007/s10143-022-01798-0. Epub 2022 May 5.
Despite advances in cerebrospinal fluid shunting technology, complications remain a significant concern. There are some contradictions about the effectiveness of proximal catheter entry sites that decrease shunt failures. We aim to compare efficiency of shunts with ventricular frontal, ventricular occipital, and cisterna magna entry sites. The systemic search was conducted in the database from conception to February 16, 2022 following guidelines of PRISMA. Between 2860 identified articles, 24 articles including 6094 patients were used for data synthesis. The aggregated results of all patients showed that "overall shunt failure rate per year" in mixed hydrocephalus with ventricular frontal and occipital shunts, and cisterna magna shunt (CMS) were 9.0%, 12.6%, and 30.7%, respectively. The corresponding values for "shunt failure rate" due to obstruction were 15.3%, 31.5%, and 10.2%, respectively. The similar results for "shunt failure rate" due to infection were 11.3%, 9.1%, and 27.2%, respectively. The related values for "shunt failure rate" due to overdrainage were 2.9%, 3.9%, and 13.6%, respectively. CMS was successful in the immediate resolution of clinical symptoms. Shunting through an occipital entry site had a greater likelihood of inaccurate catheter placement and location. Contrary to possible shunt failure due to overdrainage, the failure likelihood due to obstruction and infection in pediatric patients was higher than that of mixed hydrocephalus patients. In both mixed and pediatric hydrocephalus, obstruction and overdrainage were the most and least common complications of ventricular frontal and occipital shunts, respectively. The most and least common complications of mixed CMS were infection and obstruction, respectively.
尽管脑脊液分流技术取得了进展,但并发症仍然是一个重大问题。近端导管进入部位降低分流失败率的效果存在一些矛盾。我们旨在比较脑室额部、脑室枕部和脑池入路分流器的效率。根据 PRISMA 指南,从概念到 2022 年 2 月 16 日,在数据库中进行了系统搜索。在 2860 篇确定的文章中,有 24 篇文章包括 6094 名患者用于数据综合。所有患者的汇总结果表明,混合性脑积水伴脑室额部和枕部分流器和脑池分流器(CMS)的“每年总体分流失败率”分别为 9.0%、12.6%和 30.7%。因阻塞导致的“分流失败率”相应值分别为 15.3%、31.5%和 10.2%。因感染导致的“分流失败率”分别为 11.3%、9.1%和 27.2%。因过度引流导致的“分流失败率”分别为 2.9%、3.9%和 13.6%。CMS 可成功立即缓解临床症状。通过枕部进入部位进行分流更有可能导致导管放置和位置不准确。与可能因过度引流导致的分流失败相反,儿童患者因阻塞和感染导致的分流失败可能性高于混合性脑积水患者。在混合性和儿科脑积水中,阻塞和过度引流分别是脑室额部和枕部分流的最常见和最不常见并发症。混合性 CMS 的最常见和最不常见并发症分别是感染和阻塞。