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避免“仓促”结论:成人IgA血管炎的挑战

Avoiding "Rash" Conclusions: Challenge of IgA Vasculitis in Adults.

作者信息

Hu S, Birg A, Hovaida M, Gavin M W, McCarthy D

机构信息

Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA.

Division of Gastroenterology and Hepatology, University of New Mexico School of Medicine, 1 University of New Mexico, MSC10-5550, Albuquerque, NM, 87131, USA.

出版信息

Dig Dis Sci. 2017 Apr;62(4):874-878. doi: 10.1007/s10620-017-4505-2.

DOI:10.1007/s10620-017-4505-2
PMID:28251502
Abstract

IgA vasculitis is primarily a pediatric disease that is rarely encountered in adults. With adults, gastrointestinal manifestations are quite common, yet are nonspecific and may overlap with other diseases, particularly Crohn's disease, which can make the diagnosis a challenging task. Treatment is controversial given the disease course is usually self-limited with few serious complications. We present a case of IgA vasculitis in an adult patient with limited extraintestinal findings illustrating the complexity of arriving at the correct diagnosis.

摘要

IgA血管炎主要是一种儿科疾病,在成人中很少见。在成人中,胃肠道表现相当常见,但不具有特异性,可能与其他疾病重叠,尤其是克罗恩病,这使得诊断成为一项具有挑战性的任务。鉴于该疾病病程通常为自限性且严重并发症较少,治疗存在争议。我们报告一例成人IgA血管炎患者,其肠外表现有限,说明了做出正确诊断的复杂性。

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IgA vasculitis nephritis in children and adults: one or different entities?儿童与成人 IgA 血管炎肾炎:一种疾病还是两种不同疾病?
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本文引用的文献

1
Immunoglobulin A Vasculitis Complicated with Clostridium difficile Infection: a Rare Case Report and Brief Review of the Literature.免疫球蛋白 A 血管炎合并艰难梭菌感染:一例罕见病例报告并文献复习。
J Gastrointestin Liver Dis. 2016 Jun;25(2):235-8. doi: 10.15403/jgld.2014.1121.252.csd.
2
Terminal Ileitis as a Feature of Henoch-Schönlein Purpura Masquerading as Crohn Disease in Adults.成人中以末端回肠炎为特征的过敏性紫癜伪装成克罗恩病
J Clin Rheumatol. 2016 Mar;22(2):82-5. doi: 10.1097/RHU.0000000000000361.
3
Adult Onset Henoch-Schönlein Purpura: Case Report and Review of Literature.
成人起病的过敏性紫癜:病例报告及文献复习
Conn Med. 2015 Feb;79(2):81-5.
4
The profile of adult onset Henoch-Schönlein purpura in an Asian population.亚洲人群中成人起病的过敏性紫癜概况。
Int J Dermatol. 2015 Nov;54(11):1236-41. doi: 10.1111/ijd.12732. Epub 2015 Mar 13.
5
IgA vasculitis (Henoch-Shönlein purpura) in adults: Diagnostic and therapeutic aspects.成人 IgA 血管炎(过敏性紫癜):诊断与治疗方面。
Autoimmun Rev. 2015 Jul;14(7):579-85. doi: 10.1016/j.autrev.2015.02.003. Epub 2015 Feb 14.
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Complicated Henoch-Schönlein purpura.复杂性过敏性紫癜
J Paediatr Child Health. 2015 Jun;51(6):639-42. doi: 10.1111/jpc.12786. Epub 2014 Dec 15.
7
Differences in clinical manifestations and outcomes between adult and child patients with Henoch-Schönlein purpura.成人与儿童过敏性紫癜患者的临床表现和结局差异。
J Korean Med Sci. 2014 Feb;29(2):198-203. doi: 10.3346/jkms.2014.29.2.198. Epub 2014 Jan 28.
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Is there a crossroad between infections, genetics, and Henoch-Schönlein purpura?感染、遗传学与亨-舍二氏紫癜之间是否存在交叉路口?
Autoimmun Rev. 2013 Aug;12(10):1016-21. doi: 10.1016/j.autrev.2013.04.003. Epub 2013 May 15.
9
Mesenteric vasculitis in adults with Henoch-Schonlein purpura: a not-so-benign condition.成人过敏性紫癜合并肠系膜血管炎:并非良性疾病。
Ir J Med Sci. 2012 Jun;181(2):269-71. doi: 10.1007/s11845-009-0287-7. Epub 2009 Feb 7.
10
Endoscope images of Schönlein-Henoch purpura.过敏性紫癜的内镜图像。
Digestion. 2008;77(3-4):236-41. doi: 10.1159/000150697. Epub 2008 Aug 7.