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锝锡胶体闪烁扫描术在肾移植急性排斥反应诊断中的应用

[99mTc tin colloid scintigraphy in the diagnosis of acute rejection reactions in kidney transplants].

作者信息

Höffken H, Ebel H, Bongers H, Joseph K, Lange H

机构信息

Abteilung für klinische Nuklearmedizin, Philipps-Universität Marburg.

出版信息

Rofo. 1987 Nov;147(5):510-4. doi: 10.1055/s-2008-1048689.

Abstract

Quantitative measurements of 99MTc-tin colloid uptake in renal transplants permits differentiation of acute rejection from other causes of deteriorating renal function, such as acute tubular necrosis, cyclosporin A nephrotoxicity or chronic rejection. 144 99mTc-tin colloid scintigrams were performed on 71 renal transplants; the results were compared with clinical, biochemical and histological findings. Sensitivity of colloid scintigraphy is 97.4% and specificity is 80%. Compared with other isotope methods, this has the advantage that it does not depend on comparison with repeated examinations.

摘要

对肾移植中99MTc-锡胶体摄取进行定量测量,有助于区分急性排斥反应与肾功能恶化的其他原因,如急性肾小管坏死、环孢素A肾毒性或慢性排斥反应。对71例肾移植患者进行了144次99mTc-锡胶体闪烁扫描;将结果与临床、生化和组织学检查结果进行了比较。胶体闪烁扫描的敏感性为97.4%,特异性为80%。与其他同位素方法相比,其优点是不依赖于与重复检查结果进行比较。

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