Department of Geriatrics, Neurosciences and Orthopaedics, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore, Rome, Italy.
Department of Geriatrics, Neurosciences and Orthopaedics, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore, Rome, Italy; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
J Am Coll Cardiol. 2017 Mar 7;69(9):1188-1199. doi: 10.1016/j.jacc.2016.11.078.
Herbal medications are commonly used for clinical purposes, including the treatment of cardiovascular conditions. Compared with conventional medications, herbal medications do not require clinical studies before their marketing or formal approval from regulatory agencies, and for this reason their efficacy and safety are rarely proven. In this review, we summarize available evidence on herbal medications mostly used in cardiovascular medicine. We show that the use of these medications for the treatment of cardiovascular diseases is often not supported by scientific evidence. Despite most of these herbs showing an effect on biological mechanisms related to the cardiovascular system, data on their clinical effects are lacking. Potential relevant side effects, including increased risk of drug interactions, are described, and the possibility of contamination or substitution with other medications represents a concern. Physicians should always assess the use of herbal medications with patients and discuss the possible benefits and side effects with them.
草药通常被用于临床用途，包括心血管疾病的治疗。与传统药物相比，草药在上市前不需要进行临床研究，也不需要监管机构的正式批准，因此其疗效和安全性很少得到证实。在这篇综述中，我们总结了心血管医学中常用的草药药物的现有证据。我们表明，这些药物在治疗心血管疾病方面的应用往往没有科学证据支持。尽管这些草药中的大多数对心血管系统相关的生物机制有作用，但缺乏关于其临床效果的数据。描述了潜在的相关副作用，包括增加药物相互作用的风险，同时还存在污染或被其他药物替代的可能性。医生应该始终与患者评估草药药物的使用情况，并与他们讨论可能的益处和副作用。
