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一种新型商业培养基CHROMAgar™ mSuperCARBA™用于检测产碳青霉烯酶肠杆菌科细菌的比较评估

Comparative evaluation of a new commercial media, the CHROMAgar™ mSuperCARBA™, for the detection of carbapenemase-producing Enterobacteriaceae.

作者信息

Amar Ma'ayan, Shalom Ohad, Adler Amos

机构信息

Section of Epidemiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

Clinical Microbiology Laboratory, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

出版信息

Diagn Microbiol Infect Dis. 2017 May;88(1):20-22. doi: 10.1016/j.diagmicrobio.2017.02.004. Epub 2017 Feb 11.

DOI:10.1016/j.diagmicrobio.2017.02.004
PMID:28254249
Abstract

A new chromogenic-based medium (mSuperCARBA™) was tested for screening carbapenemase-producing Enterobacteriaceae (CPE). mSuperCARBA™ was more sensitive (83%) in detecting CPE isolates (n=69, including KPC, NDM, OXA-48, VIM, and IMI) compared with CHROMAgar™-KPC (65%) and MacConkey agar with Imipenem (69%) with comparable specificity for non carbapenemase-producing, carbapenem-resistant Enterobacteriaceae (n=29).

摘要

一种基于显色法的新型培养基（mSuperCARBA™）用于筛选产碳青霉烯酶肠杆菌科细菌（CPE）。与CHROMAgar™-KPC（65%）和含亚胺培南的麦康凯琼脂（69%）相比，mSuperCARBA™在检测CPE分离株（n = 69，包括KPC、NDM、OXA-48、VIM和IMI）时更敏感（83%），对不产碳青霉烯酶的耐碳青霉烯肠杆菌科细菌（n = 29）具有相当的特异性。

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