Service de Bactériologie-Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, K-Bicêtre, France.
J Clin Microbiol. 2012 Aug;50(8):2761-6. doi: 10.1128/JCM.06477-11. Epub 2012 Feb 22.
A Drigalski agar-based culture medium containing an ertapenem, cloxacillin, and zinc sulfate (Supercarba medium) was tested for screening carbapenemase-producing members of the family Enterobacteriaceae. OXA-48 (n = 44), NDM (n = 25), VIM or IMP (n = 27), and KPC producers (n = 18) were detected with a low detection limit. Its overall sensitivity (95.6%) was higher than those of the currently available ChromID ESBL (bioMérieux) and CHROMagar KPC (CHROMagar) screening media. The Supercarba medium provides a significant improvement for detection of the most common types of carbapenemase producers.
含厄他培南、氯唑西林和硫酸锌的 Drigalski 琼脂基础培养基（Supercarba 培养基）用于筛选产碳青霉烯酶的肠杆菌科成员。检测到 44 株 OXA-48、25 株 NDM、27 株 VIM 或 IMP 和 18 株 KPC 产酶株，检测限低。其总体敏感性（95.6%）高于目前可用的 ChromID ESBL（生物梅里埃）和 CHROMagar KPC（CHROMagar）筛选培养基。Supercarba 培养基显著提高了对最常见类型碳青霉烯酶产酶株的检测能力。
