Mayes Susan Dickerson, Calhoun Susan L, Waschbusch Daniel A, Breaux Rosanna P, Baweja Raman
Department of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.
Department of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.
Res Dev Disabil. 2017 Apr;63:28-37. doi: 10.1016/j.ridd.2017.02.012. Epub 2017 Feb 28.
DSM-5 Reactive Attachment Disorder (RAD) and Disinhibited Social Engagement Disorder (DSED) are rare, understudied, and controversial disorders.
Comorbidity in children diagnosed with RAD or DSED was compared with comorbidity in ADHD and autism to determine if RAD/DSED comorbidity differed from that for the two most common disorders in child psychiatric clinics. Samples included 4-17-year-olds, 20 with RAD and/or DSED, 933 with autism, and 895 with ADHD. Children with RAD/DSED were removed from their neglectful environments at a mean of 4 years and were a mean 10 years when studied. Mothers rated the children on the Pediatric Behavior Scale assessing oppositional behavior, conduct problems, ADHD, anxiety, depression, and other symptoms.
Five of the 20 children with RAD/DSED had DSED without RAD, 15 had RAD with DSED, and none had RAD without DSED. All children with RAD had callous-unemotional traits (CU) and 73% had conduct disorder (CD). No children with DSED-no RAD had CU or CD. Children with RAD+DSED were considerably more impaired than children with DSED-no RAD, autism, and ADHD.
Findings are consistent with other studies indicating high CD/CU comorbidity in RAD and extreme rarity of RAD without DSED, findings which are not noted in the DSM-5.
《精神疾病诊断与统计手册》第五版(DSM - 5)中的反应性依恋障碍(RAD)和去抑制性社会参与障碍(DSED)是罕见、研究不足且存在争议的疾病。
将被诊断为RAD或DSED的儿童的共病情况与注意力缺陷多动障碍(ADHD)和自闭症的共病情况进行比较,以确定RAD/DSED的共病情况是否与儿童精神科诊所中两种最常见疾病的共病情况不同。样本包括4至17岁的儿童,20名患有RAD和/或DSED,933名患有自闭症,895名患有ADHD。患有RAD/DSED的儿童平均在4岁时脱离被忽视的环境,研究时平均年龄为10岁。母亲们使用儿科行为量表对儿童的对立行为、品行问题、ADHD、焦虑、抑郁和其他症状进行评分。
20名患有RAD/DSED的儿童中,5名仅有DSED而无RAD,15名同时患有RAD和DSED,无仅有RAD而无DSED的情况。所有患有RAD的儿童都有冷酷无情特质(CU),73%有品行障碍(CD)。仅有DSED而无RAD的儿童没有CU或CD。患有RAD + DSED的儿童比仅有DSED而无RAD、自闭症和ADHD的儿童受损程度要严重得多。
研究结果与其他研究一致,表明RAD中CD/CU共病率高,且仅有RAD而无DSED的情况极为罕见,而这些情况在《精神疾病诊断与统计手册》第五版中并未提及。