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基于病例对照研究的8月龄婴儿缺铁性贫血的影响因素

[Influential factors of iron deficient anemia among infants aged 8 months based on a case-control study].

作者信息

Gao Xiao, Yan Yan, Xiang Shiting, Li Hongyan, Tan Shan, He Qiong, Sha Tingting, Liu Shiping, Zeng Guangyu, Yan Qiang

机构信息

Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.

Kaifu District Health Bureau, Changsha 410008, China.

出版信息

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2017 Feb 28;42(2):202-207. doi: 10.11817/j.issn.1672-7347.2017.02.014.

Abstract

To study the status and influential factors of iron deficient anemia (IDA) among infants aged 8 months in Changsha City.
 Methods: A case-control study was performed in this research. The case group including 105 8-month-old infants definitely diagnosed as IDA based on standardized blood test. Four-times numbers of age- and genger-matched infants without IDA were selected as a control group. Chi-square test and conditional logistic regression was used to analyze the influential factors for IDA.
 Results: The incidence rate of IDA among infants aged 8 months in Changsha City was 14.7%. The risk factors were as follows: mother with anemia in late pregnancy (OR=3.540, 95% CI 1.898 to 6.601), mixed feeding within 6 months old (OR=1.682, 95% CI 1.099 to 2.574), artificial feeding within 6 months old (OR=4.162, 95% CI 1.343 to 12.896), complementary feeding before 6 months old (OR=1.423, 95% CI 1.022 to 1.982), complementary feeding at or after 7 months old (OR=4.415, 95% CI 2.150 to 9.064), recurrent respiratory tract infections within 8 months old (OR=2.878, 95% CI 1.224 to 6.764), and repeated diarrhea within 8 months old (OR=3.710, 95% CI 1.533 to 8.980).
 Conclusion: There is certain incidence rate of IDA among infants aged 8 months in Changsha City. To prevent the IDA among infants, we should treat mothers' anemia during pregnancy, advocate scientific feeding, encourage complete breastfeeding until 6 months old, add complementary food timely and reasonably, treat infants suffering from respiratory or digestive diseases actively.

摘要

研究长沙市8月龄婴儿缺铁性贫血(IDA)的患病状况及影响因素。方法:本研究采用病例对照研究。病例组为105名经标准化血液检测确诊为IDA的8月龄婴儿。选取4倍数量的年龄和性别匹配的无IDA婴儿作为对照组。采用卡方检验和条件logistic回归分析IDA的影响因素。结果:长沙市8月龄婴儿IDA发病率为14.7%。危险因素如下:母亲孕晚期贫血(OR=3.540,95%CI 1.898至6.601)、6月龄内混合喂养(OR=1.682,95%CI 1.099至2.574)、6月龄内人工喂养(OR=4.162,95%CI 1.343至12.896)、6月龄前添加辅食(OR=1.423,95%CI 1.022至1.982)、7月龄及以后添加辅食(OR=4.415,95%CI 2.150至9.064)、8月龄内反复呼吸道感染(OR=2.878,95%CI 1.224至6.764)、8月龄内反复腹泻(OR=3.710,95%CI 1.533至8.980)。结论:长沙市8月龄婴儿IDA有一定发病率。为预防婴儿IDA,应在孕期治疗母亲贫血,提倡科学喂养,鼓励纯母乳喂养至6月龄,及时合理添加辅食,积极治疗患有呼吸道或消化道疾病的婴儿。

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