Ailanthone: a new potential drug for castration-resistant prostate cancer.
作者信息
Peng Shihong, Yi Zhengfang, Liu Mingyao
机构信息
East China Normal University and Shanghai Fengxian District Central Hospital Joint Center for Translational Medicine, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Rd, Shanghai, 200241, P.R. China.
Department of Molecular and Cellular Medicine, Center for Cancer and Stem Cell Biology, Institute of Biosciences and Technology, Texas A&M University Health Sciences Center, Houston, TX, 77030, USA.
出版信息
Chin J Cancer. 2017 Mar 3;36(1):25. doi: 10.1186/s40880-017-0194-7.
Abstract
摘要
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本文引用的文献
1
Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer.葶苈子酮通过靶向 p23 克服去势抵抗性前列腺癌中 MDV3100 的耐药性。
Nat Commun. 2016 Dec 13;7:13122. doi: 10.1038/ncomms13122.
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Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines.雄激素受体剪接变异体介导恩杂鲁胺在去势抵抗性前列腺癌细胞系中的耐药性。
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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant.在人类前列腺癌中，雄激素受体剪接变体的频繁发生导致去势抵抗。
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Molecular mechanisms of castration-resistant prostate cancer progression.去势抵抗性前列腺癌进展的分子机制。
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Quassinoids can induce mitochondrial membrane depolarisation and caspase 3 activation in human cells.苦木素类化合物可诱导人体细胞中的线粒体膜去极化和半胱天冬酶3激活。
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Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening.利用MMTV-荧光素酶报告基因和/或人雄激素受体的腺病毒转导开发两种雄激素受体检测方法用于内分泌筛查。
Toxicol Sci. 2002 Mar;66(1):82-90. doi: 10.1093/toxsci/66.1.82.
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