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中国五个省份成年男性酒精使用障碍的患病率、相关因素、共病情况及发病年龄

Prevalence, correlates, comorbidity, and age of onset of alcohol use disorders in adult males from five provinces in China.

作者信息

Phillips Michael R, Cheng Hui G, Li Xianyun, Zhang Jingxuan, Shi Qichang, Xu Guangming, Song Zhiqiang, Ding Zhijie, Pang Shutao

机构信息

Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 3210 Humin Road, Shanghai 201102, China; Departments of Psychiatry and Global Health, Emory University, 201 Dowman Drive, Atlanta, GA 30322, USA; Beijing Suicide Research and Prevention Center, WHO Collaborating Center for Research and Training in Suicide Prevention, Beijing Hui Long Guan Hospital, Beijing 100096, China.

Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 3210 Humin Road, Shanghai 201102, China; Department of Epidemiology and Biostatistics, Michigan State University, 909 Fee Rd. Room 601, East Lansing, MI 48843, USA.

出版信息

Drug Alcohol Depend. 2017 Apr 1;173:170-177. doi: 10.1016/j.drugalcdep.2016.12.026. Epub 2017 Feb 17.

Abstract

BACKGROUND

This study integrates data from high-quality mental health surveys in five provinces in China to examine the prevalence, demographic correlates, age of onset, and comorbidity of alcohol use disorder (AUD).

METHODS

The five cross-sectional surveys initially screened a representative sample of 74,752 community-living adults (94% response rate) from a sampling population including over 12% of China's adult population. Psychiatrists then administered a detailed diagnostic exam to an enriched sample of 21,015 respondents (95% response rate). The prevalence of AUD in females in China is below 0.5%, so we limited our analysis to 9619 males who completed the diagnostic interview.

RESULTS

Using meta-analyses to summarize estimates across the five locations, the current (30-day) prevalence of AUD among adult Chinese males was 9.8% (95% CI=5.7-16.9%), but there was wide cross-province variation. After adjusting for age and other demographic variables, the prevalence of AUD was significantly lower in single men than in married men (OR=0.4, CI=0.2-0.7), lower in men who were not currently working than in men who were currently working (OR=0.7, CI=0.5-0.96), and lower in men with comorbid mental disorders than in men without comorbid mental disorders (OR=0.4, CI=0.2-0.8). The risk of developing AUD peaked at 30 years of age.

CONCLUSIONS

Substantial differences in the demographic correlates and age of onset of AUD in men in China compared to those reported in other countries highlight the importance of understanding the country-specific and region-specific profile of AUD before developing intervention and prevention strategies.

摘要

背景

本研究整合了中国五个省份高质量心理健康调查的数据,以研究酒精使用障碍(AUD)的患病率、人口统计学相关性、发病年龄和共病情况。

方法

这五项横断面调查最初从一个抽样人群中筛选出74752名社区居住成年人的代表性样本(应答率为94%),该抽样人群占中国成年人口的12%以上。然后,精神科医生对21015名应答者的丰富样本进行了详细的诊断检查(应答率为95%)。中国女性中AUD的患病率低于0.5%,因此我们将分析限于9619名完成诊断访谈的男性。

结果

使用荟萃分析总结五个地点的估计值,中国成年男性中AUD的当前(30天)患病率为9.8%(95%CI=5.7-16.9%),但省份间存在很大差异。在调整年龄和其他人口统计学变量后,单身男性中AUD的患病率显著低于已婚男性(OR=0.4,CI=0.2-0.7),未就业男性低于在职男性(OR=0.7,CI=0.5-0.96),有共病精神障碍的男性低于无共病精神障碍的男性(OR=0.4,CI=0.2-0.8)。患AUD的风险在30岁时达到峰值。

结论

与其他国家报告的情况相比,中国男性中AUD的人口统计学相关性和发病年龄存在显著差异,这突出了在制定干预和预防策略之前了解AUD的国家和地区特定情况的重要性。

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