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Repair of O6-methylguanine in adapted Escherichia coli.
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Resistance of Salmonella typhimurium TA 1535 to O6-guanine methylation and mutagenesis induced by low doses of N-methyl-N'-nitro-N-nitrosoguanidine: an apparent constitutive repair activity.
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Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
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Cytotoxicity, mutations and SCEs induced by methylating agents are reduced in CHO cells expressing an active mammalian O6-methylguanine-DNA methyltransferase gene.
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Relationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes.
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Changes in O6-methylguanine disappearance from rat liver DNA during chronic dimethylnitrosamine administration. A possible similarity between the system removing O6-methylguanine from DNA in rat liver and in Escherichia coli adapted to N-methyl-N'-nitro-N-nitrosoguanidine.
Chem Biol Interact. 1980 Aug;31(2):239-45. doi: 10.1016/0009-2797(80)90012-5.
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Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA.
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Expression of the inactive C145A mutant human O6-alkylguanine-DNA alkyltransferase in E.coli increases cell killing and mutations by N-methyl-N'-nitro-N-nitrosoguanidine.
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Roles of transcription and repair in alkylation mutagenesis.
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引用本文的文献
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Dynamic basis for dA•dGTP and dA•d8OGTP misincorporation via Hoogsteen base pairs.
Nat Chem Biol. 2023 Jul;19(7):900-910. doi: 10.1038/s41589-023-01306-5. Epub 2023 Apr 24.
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Thermoadaptation of alpha-galactosidase AgaB1 in Thermus thermophilus.
J Bacteriol. 2002 Jun;184(12):3385-91. doi: 10.1128/JB.184.12.3385-3391.2002.
3
Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli.
EMBO J. 1994 Apr 1;13(7):1495-501. doi: 10.1002/j.1460-2075.1994.tb06410.x.
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Effect of ogt expression on mutation induction by methyl-, ethyl- and propylmethanesulphonate in Escherichia coli K12 strains.
Mol Gen Genet. 1994 Mar;242(6):744-8. doi: 10.1007/BF00283431.
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Effect of partial hepatectomy on removal of O6-methylguanine from alkylated DNA by rat liver extracts.
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Adaptive increase of O6-methylguanine-acceptor protein in HeLa cells following N-methyl-N'-nitro-N-nitrosoguanidine treatment.
Nucleic Acids Res. 1982 Aug 11;10(15):4595-604. doi: 10.1093/nar/10.15.4595.
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Genetic mapping of ada and adc mutations affecting the adaptive response of Escherichia coli to alkylating agents.
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Isolation of mutants of Escherichia coli with increased resistance to alkylating agents: mutants deficient in thiols and mutants constitutive for the adaptive response.
Mol Gen Genet. 1980;180(1):85-90. doi: 10.1007/BF00267355.
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Cell-specific differences in O6-alkylguanine DNA repair activity during continuous exposure to carcinogen.
Proc Natl Acad Sci U S A. 1982 Sep;79(18):5499-502. doi: 10.1073/pnas.79.18.5499.
10
Repair of O6-ethylguanine in DNA by a chromatin fraction from rat liver: transfer of the ethyl group to an acceptor protein.
Proc Natl Acad Sci U S A. 1981 Nov;78(11):6766-70. doi: 10.1073/pnas.78.11.6766.
本文引用的文献
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Three loci in Escherichia coli K-12 that control the excision of pyrimidine dimers and certain other mutagen products from DNA.
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Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N'-nitro-N-nitrosoguanidine.
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The properties of O 6 -methylguanine in templates for RNA polymerase.
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Evidence that pretreatment of Escherichia coli cells with N-methyl-N'-nitro-N-nitrosoguanidine enhances mutability of subsequently infecting phage lambda.
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Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.
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Dimethylnitrosamine inhibits enzymatic removal of O6-methylguanine from DNA.
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Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli.
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An adaptive response of E. coli to low levels of alkylating agent: comparison with previously characterised DNA repair pathways.
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Mechanism of ultraviolet-induced mutagenesis: extent and fidelity of in vitro DNA synthesis on irradiated templates.
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