Steinert P M, Zimmerman S B, Starger J M, Goldman R D
Proc Natl Acad Sci U S A. 1978 Dec;75(12):6098-101. doi: 10.1073/pnas.75.12.6098.
The 10-nm filaments of baby hamster kidney (BHK-21) cells, when examined either in the form of native filament caps or polymerized in vitro, are long tubes of protein 8--10 nm in diameter. They contain about 42% alpha-helix, which, on the basis of x-ray diffraction data, is arranged in a coiled-coil conformation characteristic of proteins of the alpha type. The known structural properties such as morphology, dimensions, subunit composition, and ultrastructure of this fibrous protein are very similar to those of the mammalian epidermal keratin filament, to which it may therefore be related.
幼仓鼠肾（BHK - 21）细胞的10纳米细丝，无论是以天然细丝帽的形式进行检测，还是在体外聚合时，都是直径为8 - 10纳米的蛋白质长管。它们含有约42%的α - 螺旋，根据X射线衍射数据，这些α - 螺旋以α型蛋白质特有的卷曲螺旋构象排列。这种纤维状蛋白质的已知结构特性，如形态、尺寸、亚基组成和超微结构，与哺乳动物表皮角蛋白细丝非常相似，因此它们可能存在关联。
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