van Vliet Majogé, Huisman Martijn, Deeg Dorly J H
Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands.
EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.
J Am Geriatr Soc. 2017 Jun;65(6):1214-1221. doi: 10.1111/jgs.14767. Epub 2017 Mar 6.
To examine the effects of decreasing hospital length of stay (HLOS) on change in functioning from prehospital admission to posthospital discharge in older cohorts.
Cohort-sequential design.
Nationwide, older population-based Longitudinal Aging Study Amsterdam (LASA).
Individuals aged 68 and older with any hospital admission according to national medical registry data: two 10-year age groups (68-77 (younger-old) and 78-87 (older-old)) in two periods (1996-99 (Period 1) and 2006-09 (Period 2)) (N = 1,212).
HLOS was the main independent variable in multinomial logistic models, dichotomized as 1 to 5 days (short) and 6 days or longer (long). Outcomes were change scores in mobility and activities in daily living (ADLs). Respondents who died during the 3-year period were assigned to a third outcome category.
Results for both age groups showed more hospital admissions and shorter median HLOS in Period 2 than Period 1 (P < .05). Lower odds of decline in physical functioning were found in respondents with short HLOS than in those with long HLOS (for mobility: odds ratio (OR) = 0.36, 95% confidence interval (CI) = 0.23-0.54 (younger-old) and OR = 0.47, 95% CI = 0.30-0.72 (older-old); for ADLs: OR = 0.30, 95% CI = 0.19-0.48 (younger-old) and OR = 0.30, 95% CI = 0.18-0.53 (older-old)). Adjusting for confounders did not significantly change these estimates. Period did not modify these associations.
Because the associations of HLOS with change in mobility and ADLs were the same in both periods, hospitalized older adults had neither advantage nor disadvantage from the decrease in HLOS. In addition, in both age groups, a greater percentage experienced the better functional outcomes and lower mortality associated with short admissions, which suggests an advantage of the decrease in HLOS.
研究缩短老年人群住院时长(HLOS)对其从入院前到出院后功能变化的影响。
队列序贯设计。
基于全国老年人群的阿姆斯特丹纵向衰老研究(LASA)。
根据国家医疗登记数据,68岁及以上的任何住院患者:两个10岁年龄组(68 - 77岁(年轻老人)和78 - 87岁(年长老人)),分两个时期(1996 - 1999年(时期1)和2006 - 2009年(时期2))(N = 1212)。
HLOS是多项逻辑模型中的主要自变量,分为1至5天(短)和6天或更长时间(长)。结果是 mobility 和日常生活活动(ADL)的变化得分。在3年期间死亡的受访者被归为第三个结果类别。
两个年龄组的结果均显示,时期2的住院次数多于时期1,且中位HLOS短于时期1(P < 0.05)。HLOS短的受访者身体功能下降的几率低于HLOS长的受访者(对于mobility:优势比(OR)= 0.36,95%置信区间(CI)= 0.23 - 0.54(年轻老人),OR = 0.47,95% CI = 0.30 - 0.72(年长老人);对于ADL:OR = 0.30,95% CI = 0.19 - 0.48(年轻老人),OR = 0.30,95% CI = 0.18 - 0.53(年长老人))。对混杂因素进行调整后,这些估计值没有显著变化。时期并未改变这些关联。
由于HLOS与mobility和ADL变化之间的关联在两个时期相同,住院的老年人并未因HLOS的缩短而受益或受损。此外,在两个年龄组中,更大比例的人经历了与短住院相关的更好的功能结局和更低的死亡率,这表明HLOS缩短具有优势。