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与空肠弯曲菌抗原变异相关的基因组重排

Genomic rearrangements associated with antigenic variation in Campylobacter coli.

作者信息

Guerry P, Logan S M, Trust T J

机构信息

Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20814.

出版信息

J Bacteriol. 1988 Jan;170(1):316-9. doi: 10.1128/jb.170.1.316-319.1988.

DOI:10.1128/jb.170.1.316-319.1988
PMID:2826396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC210644/
Abstract

Campylobacter coli and Campylobacter jejuni share a limited number of highly conserved DNA sequences with members of the family Enterobacteriaceae. One of these sequences was cloned from C. coli VC167, and the region of homology to the enteric sequences was determined to be confined to a 700-base-pair region. The DNA represented in this clone undergoes a programmed, reversible rearrangement in VC167 that is associated with flagellar antigenic variation.

摘要

空肠弯曲菌和结肠弯曲菌与肠杆菌科成员共享数量有限的高度保守DNA序列。其中一个序列是从结肠弯曲菌VC167中克隆出来的，与肠道序列的同源区域被确定局限于一个700个碱基对的区域。该克隆中所代表的DNA在VC167中经历一种程序性的、可逆的重排，这与鞭毛抗原变异有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/017c/210644/f51924774d58/jbacter00179-0336-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/017c/210644/d72e21164646/jbacter00179-0335-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/017c/210644/1fd6ceff59fd/jbacter00179-0336-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/017c/210644/f51924774d58/jbacter00179-0336-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/017c/210644/d72e21164646/jbacter00179-0335-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/017c/210644/1fd6ceff59fd/jbacter00179-0336-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/017c/210644/f51924774d58/jbacter00179-0336-b.jpg

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本文引用的文献

1
'1001' Campylobacters: cultural characteristics of intestinal campylobacters from man and animals.“1001” 弯曲杆菌：人和动物肠道弯曲杆菌的培养特性
J Hyg (Lond). 1980 Dec;85(3):427-42. doi: 10.1017/s0022172400063506.
2
Involvement of a plasmid in the invasive ability of Shigella flexneri.一种质粒与福氏志贺菌侵袭能力的关系。
Infect Immun. 1982 Mar;35(3):852-60. doi: 10.1128/iai.35.3.852-860.1982.
3
Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate.
从德国犬猫中分离出的犬空肠弯曲菌和瑞士弯曲菌菌株的基因组异质性和O抗原多样性。
J Clin Microbiol. 2001 Jul;39(7):2548-57. doi: 10.1128/JCM.39.7.2548-2557.2001.
4
A genetic locus involved in iron utilization unique to some Campylobacter strains.某些弯曲杆菌菌株特有的与铁利用相关的基因座。
J Bacteriol. 1997 Jun;179(12):3997-4002. doi: 10.1128/jb.179.12.3997-4002.1997.
5
Molecular cloning and site-specific mutagenesis of a gene involved in arylsulfatase production in Campylobacter jejuni.空肠弯曲菌中参与芳基硫酸酯酶产生的基因的分子克隆和位点特异性诱变。
J Bacteriol. 1996 Jun;178(11):3335-8. doi: 10.1128/jb.178.11.3335-3338.1996.
6
Development and characterization of recA mutants of Campylobacter jejuni for inclusion in attenuated vaccines.用于减毒疫苗的空肠弯曲菌recA突变体的开发与特性分析。
Infect Immun. 1994 Feb;62(2):426-32. doi: 10.1128/iai.62.2.426-432.1994.
7
Phylogenetic and molecular characterization of a 23S rRNA gene positions the genus Campylobacter in the epsilon subdivision of the Proteobacteria and shows that the presence of transcribed spacers is common in Campylobacter spp.23S rRNA基因的系统发育和分子特征将弯曲杆菌属定位在变形菌门的ε亚纲中，并表明转录间隔区在弯曲杆菌属物种中普遍存在。
J Bacteriol. 1994 Aug;176(15):4597-609. doi: 10.1128/jb.176.15.4597-4609.1994.
8
Expression of multiple flagellin-encoding genes of Proteus mirabilis.奇异变形杆菌多个鞭毛蛋白编码基因的表达
J Bacteriol. 1994 Dec;176(23):7169-81. doi: 10.1128/jb.176.23.7169-7181.1994.
9
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J Bacteriol. 1995 Oct;177(20):5959-70. doi: 10.1128/jb.177.20.5959-5970.1995.
10
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Infect Immun. 1989 Aug;57(8):2583-5. doi: 10.1128/iai.57.8.2583-2585.1989.
编码来自一株尿路感染大肠杆菌分离株的1型或D-甘露糖抗性菌毛的重组质粒的构建与表达
Infect Immun. 1981 Sep;33(3):933-8. doi: 10.1128/iai.33.3.933-938.1981.
4
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Am J Vet Res. 1969 Aug;30(8):1437-42.
5
Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli.生长条件对大肠杆菌中超螺旋ColE1脱氧核糖核酸与蛋白质松弛复合体形成的影响。
J Bacteriol. 1972 Jun;110(3):1135-46. doi: 10.1128/jb.110.3.1135-1146.1972.
6
Reversible expression of flagella in Campylobacter jejuni.空肠弯曲菌鞭毛的可逆表达
Infect Immun. 1985 Dec;50(3):941-3. doi: 10.1128/iai.50.3.941-943.1985.
7
Campylobacter pylori, the spiral bacterium associated with human gastritis, is not a true Campylobacter sp.幽门螺杆菌，这种与人类胃炎相关的螺旋状细菌，并非真正的弯曲菌属细菌。
J Bacteriol. 1987 May;169(5):2137-41. doi: 10.1128/jb.169.5.2137-2141.1987.
8
Programmed gene rearrangements altering gene expression.改变基因表达的程序性基因重排。
Science. 1987 Feb 6;235(4789):658-67. doi: 10.1126/science.3544215.
9
Opacity genes in Neisseria gonorrhoeae: control of phase and antigenic variation.淋病奈瑟菌中的不透明基因：相位和抗原变异的控制
Cell. 1986 Oct 10;47(1):61-71. doi: 10.1016/0092-8674(86)90366-1.
10
Gene conversion involving the pilin structural gene correlates with pilus+ in equilibrium with pilus- changes in Neisseria gonorrhoeae.涉及菌毛蛋白结构基因的基因转换与淋病奈瑟菌中菌毛阳性与菌毛阴性平衡变化相关。
Cell. 1986 Oct 24;47(2):267-76. doi: 10.1016/0092-8674(86)90449-6.