与空肠弯曲菌抗原变异相关的基因组重排
Genomic rearrangements associated with antigenic variation in Campylobacter coli.
作者信息
Guerry P, Logan S M, Trust T J
机构信息
Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20814.
出版信息
J Bacteriol. 1988 Jan;170(1):316-9. doi: 10.1128/jb.170.1.316-319.1988.
Campylobacter coli and Campylobacter jejuni share a limited number of highly conserved DNA sequences with members of the family Enterobacteriaceae. One of these sequences was cloned from C. coli VC167, and the region of homology to the enteric sequences was determined to be confined to a 700-base-pair region. The DNA represented in this clone undergoes a programmed, reversible rearrangement in VC167 that is associated with flagellar antigenic variation.
空肠弯曲菌和结肠弯曲菌与肠杆菌科成员共享数量有限的高度保守DNA序列。其中一个序列是从结肠弯曲菌VC167中克隆出来的，与肠道序列的同源区域被确定局限于一个700个碱基对的区域。该克隆中所代表的DNA在VC167中经历一种程序性的、可逆的重排，这与鞭毛抗原变异有关。
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