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弯曲杆菌鞭毛蛋白的体内抗原变异

In vivo antigenic variation of Campylobacter flagellin.

作者信息

Logan S M, Guerry P, Rollins D M, Burr D H, Trust T J

机构信息

Department of Biochemistry and Microbiology, University of Victoria, British Columbia, Canada.

出版信息

Infect Immun. 1989 Aug;57(8):2583-5. doi: 10.1128/iai.57.8.2583-2585.1989.

DOI:10.1128/iai.57.8.2583-2585.1989
PMID:2744863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC313492/
Abstract

Campylobacter coli VC167 cells producing either antigenic phase 1 (P1) or phase 2 (P2) flagellins (as determined by characteristic protein and DNA patterns) were used to infect rabbits by the removable intestinal tie-adult rabbit diarrhea (RITARD) procedure. Rabbits infected with P2 cells shed predominantly P2 cells throughout the infection; in rabbits infected with P1 cells, a transition of fecal isolates from P1 to P2 was observed.

摘要

产生抗原1期(P1)或2期(P2)鞭毛蛋白的空肠弯曲菌VC167细胞(由特征性蛋白质和DNA模式确定)通过可移除肠结扎-成年兔腹泻(RITARD)程序用于感染兔子。感染P2细胞的兔子在整个感染过程中主要排出P2细胞;在感染P1细胞的兔子中,观察到粪便分离物从P1向P2的转变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a60/313492/4cf6a9440ef9/iai00068-0330-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a60/313492/4cf6a9440ef9/iai00068-0330-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a60/313492/4cf6a9440ef9/iai00068-0330-a.jpg

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In vivo antigenic variation of Campylobacter flagellin.弯曲杆菌鞭毛蛋白的体内抗原变异
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本文引用的文献

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Kinetics of early cholera infection in the removable intestinal tie-adult rabbit diarrhea model.可移除肠道结扎-成年兔腹泻模型中霍乱早期感染的动力学
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Simple adult rabbit model for Vibrio cholerae and enterotoxigenic Escherichia coli diarrhea.用于霍乱弧菌和产肠毒素大肠杆菌腹泻的简易成年兔模型。
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Role of two flagellin genes in Campylobacter motility.两个鞭毛蛋白基因在弯曲杆菌运动性中的作用。
J Bacteriol. 1991 Aug;173(15):4757-64. doi: 10.1128/jb.173.15.4757-4764.1991.
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Antigenic differences among Campylobacter fetus S-layer proteins.胎儿弯曲杆菌S层蛋白之间的抗原差异。
J Bacteriol. 1990 Sep;172(9):5035-43. doi: 10.1128/jb.172.9.5035-5043.1990.
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Variation in antigenicity and molecular weight of Campylobacter coli VC167 flagellin in different genetic backgrounds.不同遗传背景下空肠弯曲菌VC167鞭毛蛋白的抗原性和分子量变异
J Bacteriol. 1992 Jul;174(13):4230-8. doi: 10.1128/jb.174.13.4230-4238.1992.
10
Biochemical and antigenic properties of the Campylobacter flagellar hook protein.弯曲杆菌鞭毛钩蛋白的生化和抗原特性
J Bacteriol. 1992 Jun;174(12):3874-83. doi: 10.1128/jb.174.12.3874-3883.1992.
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Simple adult rabbit model for Campylobacter jejuni enteritis.空肠弯曲菌肠炎的简易成年兔模型。
Infect Immun. 1983 Dec;42(3):1176-82. doi: 10.1128/iai.42.3.1176-1182.1983.
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Campylobacter jejuni enteritis; a review.空肠弯曲菌肠炎综述
Trop Geogr Med. 1984 Sep;36(3):215-22.
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Flagella help Salmonella typhimurium survive within murine macrophages.鞭毛有助于鼠伤寒沙门氏菌在小鼠巨噬细胞内存活。
Infect Immun. 1984 Dec;46(3):819-25. doi: 10.1128/iai.46.3.819-825.1984.
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