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序贯器官衰竭评估评分可预测冠状动脉旁路移植术后的死亡率。

Sequential organ failure assessment score predicts mortality after coronary artery bypass grafting.

作者信息

Chang Chih-Hsiang, Chen Shao-Wei, Fan Pei-Chun, Lee Cheng-Chia, Yang Huang-Yu, Chang Su-Wei, Pan Heng-Chih, Tsai Feng-Chun, Yang Chih-Wei, Chen Yung-Chang

机构信息

Kidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.

School of medicine, College of Medicine, Chang Gung University, 199 Tung Hwa North Road, Taoyuan, Taipei, 105, Taiwan.

出版信息

BMC Surg. 2017 Mar 6;17(1):22. doi: 10.1186/s12893-017-0219-9.

Abstract

BACKGROUND

Mortality after coronary artery bypass grafting (CABG) is generally associated with underlying disease and surgical factors overlooked in preoperative prognostic models. Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE II) scores are widely used in intensive care units for outcome prediction. This study investigated the accuracy of these models in predicting mortality.

METHODS

Between January 2010 and April 2013, 483 patients who underwent isolated CABG were enrolled. The clinical characteristics, outcomes, and prognostic model scores of the patients were collected. Discrimination was assessed using the area under the curve approach.

RESULTS

Both SOFA and APACHE II scores were effective for predicting in-hospital mortality. Among the organ systems examined in the SOFA, the cardiac and renal systems were the strongest predictors of CABG mortality. Multivariate analysis identified only the SOFA score as being an independent risk factor for mortality.

CONCLUSION

In summary, the SOFA score can be used to accurately identify mortality after isolated CABG.

摘要

背景

冠状动脉旁路移植术(CABG)后的死亡率通常与术前预后模型中被忽视的基础疾病和手术因素有关。序贯器官衰竭评估(SOFA)和急性生理与慢性健康状况评估(APACHE II)评分在重症监护病房中广泛用于预测预后。本研究调查了这些模型在预测死亡率方面的准确性。

方法

在2010年1月至2013年4月期间,纳入了483例行单纯CABG的患者。收集患者的临床特征、结局和预后模型评分。使用曲线下面积法评估辨别力。

结果

SOFA和APACHE II评分均能有效预测住院死亡率。在SOFA中检查的器官系统中,心脏和肾脏系统是CABG死亡率最强的预测因素。多变量分析仅确定SOFA评分是死亡率的独立危险因素。

结论

总之,SOFA评分可用于准确识别单纯CABG后的死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa29/5339985/30d0eb4d3ce9/12893_2017_219_Fig1_HTML.jpg

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