Lopez A F, Sanderson C J, Gamble J R, Campbell H D, Young I G, Vadas M A
Division of Human Immunology, Institute of Medical and Veterinary Science, Adelaide, South Australia.
J Exp Med. 1988 Jan 1;167(1):219-24. doi: 10.1084/jem.167.1.219.
Human rIL-5 was found to selectively stimulate morphological changes and the function of human eosinophils. This molecule is thus a prime candidate for the selective eosinophilia and eosinophil activation seen in disease.
人们发现重组人白细胞介素-5(rIL-5)能选择性地刺激人类嗜酸性粒细胞的形态变化及其功能。因此,该分子是疾病中出现的选择性嗜酸性粒细胞增多和嗜酸性粒细胞激活的主要候选因素。