Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:1127-1130. doi: 10.1109/EMBC.2016.7590902.
Attention deficit hyperactivity disorder (ADHD) is a common psychological disorder for a broad range of ages. Child and adolescent ADHD patients show different behavior patterns. The differences between child and adolescent ADHD patients have not been fully explored in terms of brain connectivity. In this study, we explored the differences of connectivity patterns between child and adolescent ADHD patients using resting-state functional magnetic resonance imaging (rs-fMRI) of 52 ADHD patients (26 children and 26 adolescents). Default mode network and frontoparietal network showed significant group-wise connectivity pattern differences between child and adolescent ADHD patients. The results of our study might suggest potential imaging biomarkers for further ADHD related studies.
注意缺陷多动障碍(ADHD)是一种在广泛年龄段中常见的心理障碍。儿童和青少年ADHD患者表现出不同的行为模式。在大脑连通性方面,儿童和青少年ADHD患者之间的差异尚未得到充分探索。在本研究中,我们使用52名ADHD患者(26名儿童和26名青少年)的静息态功能磁共振成像(rs-fMRI)来探索儿童和青少年ADHD患者之间连通性模式的差异。默认模式网络和额顶网络在儿童和青少年ADHD患者之间显示出显著的组间连通性模式差异。我们的研究结果可能为进一步的ADHD相关研究提示潜在的影像学生物标志物。