利用麦克风的共振特性进行体外葡萄糖浓度测量的光声光谱法。

Photoacoustic spectroscopy that uses a resonant characteristic of a microphone for in vitro measurements of glucose concentration.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:4861-4864. doi: 10.1109/EMBC.2016.7591816.

DOI:10.1109/EMBC.2016.7591816

Abstract

Glucose measurements using photoacoustic spectroscopy have been highlighted to be a modality for non-invasive glucose monitoring. Previous photoacoustic spectroscopy for glucose measurements have used a resonant acoustic cell with a broadband capacitive microphone to increase sensitivity. However, a resonant characteristic of a microphone has not been investigated yet due to the working frequency range much lower than the resonance frequency of the microphone membrane. We, here, present a photoacoustic spectroscopy system that utilizes an ultrasound resonance of a microphone to increase sensitivity. We found that matching the resonance of a photoacoustic cell with the resonance of a microphone can increase signal-to-noise ratio and our system can distinguish the glucose concentration in liquid.

摘要

利用光声光谱法进行葡萄糖测量已被视为一种用于无创血糖监测的方式。先前用于葡萄糖测量的光声光谱法采用了带有宽带电容式麦克风的共振声学池来提高灵敏度。然而，由于工作频率范围远低于麦克风膜片的共振频率，麦克风的共振特性尚未得到研究。在此，我们展示了一种利用麦克风的超声共振来提高灵敏度的光声光谱系统。我们发现使光声池的共振与麦克风的共振相匹配可以提高信噪比，并且我们的系统能够区分液体中的葡萄糖浓度。