Kito Shinsuke
Department of Psychiatry and Advanced Medical Technology, National Center Hospital, National Center of Neurology and Psychiatry.
Brain Nerve. 2017 Mar;69(3):239-246. doi: 10.11477/mf.1416200733.
In Japan, approximately one million patients currently receive medical treatment for mood disorders. However, there are only a few available treatments for patients with treatment-resistant depression or bipolar depression. Repetitive transcranial magnetic stimulation (rTMS), a neuromodulation technique, has proven to be effective for treatment-resistant depression, and also has a potential therapeutic efficacy in patients with bipolar depression who do not respond to medication. Magnetic seizure therapy (MST) is an experimental technique for introducing a seizure by using rTMS, which demonstrates a therapeutic efficacy similar to that of electroconvulsive therapy (ECT), but with fewer cognitive side effects.
在日本,目前约有100万患者接受情绪障碍的医学治疗。然而,对于难治性抑郁症或双相抑郁症患者,可用的治疗方法却很少。重复经颅磁刺激(rTMS)是一种神经调节技术,已被证明对难治性抑郁症有效,并且对药物治疗无反应的双相抑郁症患者也具有潜在的治疗效果。磁休克治疗(MST)是一种通过使用rTMS引发癫痫发作的实验技术,其显示出与电休克治疗(ECT)相似的治疗效果,但认知副作用较少。