Majerus P W, Connolly T M, Ross T S, Ishii H, Deckmyn H
Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110.
Symp Fundam Cancer Res. 1986;39:157-63.
The phosphoinositides are minor phospholipids present in all eukaryotic cells. They are storage forms for messenger molecules that function in the transmission of signals across the cell membrane and evoke responses to extracellular agonists. The phosphoinositides break down to liberate messenger molecules or precursors of messenger molecules. Many different compounds are formed, although the functions of only a few are understood currently.
磷酸肌醇是存在于所有真核细胞中的微量磷脂。它们是信使分子的储存形式,这些信使分子在跨细胞膜的信号传递中发挥作用,并引发对细胞外激动剂的反应。磷酸肌醇分解以释放信使分子或信使分子的前体。虽然目前仅了解少数几种化合物的功能,但会形成许多不同的化合物。