Moran Ellen M, Foley Ruth, Powell Frank C
Education and Research Centre, St. Vincent's University Hospital, Dublin, Ireland.
The Charles Institute of Dermatology, University College Dublin, Dublin, Ireland.
Clin Dermatol. 2017 Mar-Apr;35(2):195-200. doi: 10.1016/j.clindermatol.2016.10.014. Epub 2016 Oct 27.
Demodex mites are part of the vast microbiome living on and within human skin. The interaction of the various microorganisms with the skin plays a key role in the maintenance of homeostasis. The precise role and function of Demodex mites within normal and diseased human skin remains elusive. The emergence of ivermectin as a key therapy for rosacea has refocused interest in the role of Demodex mites in the pathogenesis of this skin disease and the ability of Demodex to modulate the host immune system.
蠕形螨是生活在人类皮肤表面及皮肤内的庞大微生物群落的一部分。各种微生物与皮肤的相互作用在维持体内平衡中起着关键作用。蠕形螨在正常和患病人类皮肤中的精确作用和功能仍不清楚。伊维菌素作为治疗酒渣鼻的关键药物的出现，重新引发了人们对蠕形螨在这种皮肤病发病机制中的作用以及蠕形螨调节宿主免疫系统能力的关注。
