Zhang Ting, Liu Xu, Yang Fengjuan, Xu Yuanyuan, Jiang Xian
Department of Dermatology, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Clin Cosmet Investig Dermatol. 2023 Oct 13;16:2855-2862. doi: 10.2147/CCID.S429099. eCollection 2023.
The pathogenesis of COVID-19 includes systemic immune activation and endothelial dysfunction, which is closely related to the pathogenesis of rosacea. In order to investigate the influence of COVID-19 infection on the condition of rosacea patients, we retrospectively investigated the impact of COVID-19 infection and COVID-19-related masks on rosacea patients.
We collected the basic information from rosacea patients who had a long-term follow-up at West China Hospital of Sichuan University. Between January 2023 and March 2023, we recruited 87 rosacea patients for this survey.
Our results showed that COVID-19 infection could aggravate the condition of rosacea patients, and the change in the symptoms was not related to fever, temperature, antipyretics use, and vaccination. In addition, we observed a significant association between the type of mask worn by rosacea patients and exacerbation, while the duration of mask usage did not exhibit a similar relationship.
Considering the ongoing global utilization of masks due to the COVID-19 pandemic and the possible recurrence of COVID-19 infection, dermatologists should monitor the condition of rosacea patients infected with COVID-19 and adjust the treatment regimens accordingly.
新型冠状病毒肺炎（COVID-19）的发病机制包括全身免疫激活和内皮功能障碍，这与酒渣鼻的发病机制密切相关。为了研究COVID-19感染对酒渣鼻患者病情的影响，我们回顾性调查了COVID-19感染及与COVID-19相关的口罩对酒渣鼻患者的影响。
我们收集了在四川大学华西医院进行长期随访的酒渣鼻患者的基本信息。在2023年1月至2023年3月期间，我们招募了87名酒渣鼻患者参与此次调查。
我们的结果表明，COVID-19感染会加重酒渣鼻患者的病情，症状变化与发热、体温、退烧药使用及疫苗接种无关。此外，我们观察到酒渣鼻患者佩戴的口罩类型与病情加重之间存在显著关联，而口罩使用时长未呈现类似关系。
鉴于COVID-19大流行导致全球持续使用口罩以及COVID-19感染可能复发，皮肤科医生应监测感染COVID-19的酒渣鼻患者的病情，并相应调整治疗方案。
