柬埔寨农村地区不同HemoCue设备及设备操作人员之间血红蛋白测量结果的差异。
Variation in haemoglobin measurement across different HemoCue devices and device operators in rural Cambodia.
作者信息
Rappaport Aviva I, Barr Susan I, Green Timothy J, Karakochuk Crystal D
机构信息
Department of Food, Nutrition and Health, University of British Columbia, Vancouver, British Columbia, Canada.
South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
出版信息
J Clin Pathol. 2017 Jul;70(7):615-618. doi: 10.1136/jclinpath-2017-204351. Epub 2017 Mar 8.
UNLABELLED
: Point-of-use haemoglobinometers, such as the HemoCue, are a common method to measure haemoglobin (Hb) concentration in field settings as the device is portable, requires only a small finger-prick capillary blood sample and computes an immediate Hb reading. The aim of this study was to compare Hb measurements across different HemoCue devices and across device operators using capillary blood samples collected from women during a trial in rural Cambodia. We compared mean±SD capillary Hb concentration (g/L) across n=12 different HemoCue Hb 301 devices and across n=9 device operators among 2846 Cambodian women. Significant variability in mean Hb concentration was observed across HemoCue devices (means ranged from 117 to 124 g/L) and across device operators (means ranged from 118 to 124 g/L). This variability is of particular concern when a single HemoCue device or device operator is used at different time points in surveys or research trials.
TRIAL REGISTRATION NUMBER
NCT02481375.
未标注
即时血红蛋白仪，如HemoCue，是在现场环境中测量血红蛋白（Hb）浓度的常用方法，因为该设备便于携带，仅需采集一小份手指末梢毛细血管血样，并能即时计算出血红蛋白读数。本研究的目的是在柬埔寨农村的一项试验中，比较使用从女性身上采集的毛细血管血样时，不同HemoCue设备以及不同设备操作人员之间的血红蛋白测量值。我们比较了2846名柬埔寨女性中n = 12台不同的HemoCue Hb 301设备以及n = 9名设备操作人员的平均±标准差毛细血管血红蛋白浓度（g/L）。在HemoCue设备之间（平均值范围为117至124 g/L）以及设备操作人员之间（平均值范围为118至124 g/L）均观察到平均血红蛋白浓度存在显著差异。当在调查或研究试验的不同时间点使用单一的HemoCue设备或设备操作人员时，这种差异尤其值得关注。
试验注册号
NCT02481375。
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