Jung Woo Jin, Park Su Min, Park Jong Man, Rhee Harin, Kim Il Young, Lee Dong Won, Lee Soo Bong, Seong Eun Young, Kwak Ihm Soo, Song Sang Heon
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.; Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Electrolyte Blood Press. 2016 Dec;14(2):27-30. doi: 10.5049/EBP.2016.14.2.27. Epub 2016 Dec 31.
This report describes a case of severe hypernatremia with a serum sodium concentration of 188.1mmol/L caused by exogenous salt intake. A 26-year-old man diagnosed with Crohn's disease 5 years previously visited our clinic due to generalized edema and personality changes, with aggressive behavior. He had compulsively consumed salts, ingesting approximately 154 g of salt over the last 4 days. Despite careful fluid management that included not only hypotonic fluid therapy for 8 hours but also hypertonic saline administration, his serum sodium level decreased sharply at 40.6 mmol/L; however, it returned to normal within 72-hour of treatment without any neurological deficits. Primary hypothyroidism was also diagnosed. He was discharged after 9 days from admission, with a stable serum sodium level. We have described the possibility of successful treatment in a patient with hypernatremia caused by acute salt intoxication without sustained hypotonic fluid therapy.
本报告描述了一例因外源性盐摄入导致血清钠浓度达188.1mmol/L的严重高钠血症病例。一名5年前被诊断为克罗恩病的26岁男性因全身水肿和性格改变、出现攻击性行为前来我院就诊。他强迫性地摄入盐分，在过去4天内摄入了约154克盐。尽管进行了精心的液体管理，包括8小时的低渗液体治疗以及高渗盐水给药，但他的血清钠水平急剧下降了40.6mmol/L；然而，在治疗72小时内恢复正常，且无任何神经功能缺损。同时还诊断出原发性甲状腺功能减退症。入院9天后患者出院，血清钠水平稳定。我们描述了在急性盐中毒引起的高钠血症患者中，不进行持续低渗液体治疗而成功治疗的可能性。
