Creatine kinase isoenzymes in the confirmation of acute myocardial infarction.

Serum MB isoenzyme of creatine kinase is the most specific and sensitive indicator of myocardial infarction. Despite these virtues, its clinical use is handicapped by rapid normalization after the onset of myocardial injury. In patients suffering brain accidents, the increase of serum CK-MB isoenzymes indicates stimultaneous myocardial damage and means poor prognosis.