寻找微生物的工作击中要害。
Microbe Hunting Hits Home.
作者信息
Ivanov Ivaylo I
机构信息
Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
出版信息
Cell Host Microbe. 2017 Mar 8;21(3):282-285. doi: 10.1016/j.chom.2017.02.010.
Abstract
Ten years ago, we discovered that microbiota composition controls intestinal T cell homeostasis and alters T cell responses of mice in different animal facilities. Here I discuss how these discoveries, reported in Cell Host & Microbe in 2008, came to be and contributed to our understanding of microbiota immune effects.
摘要
十年前，我们发现微生物群组成控制肠道T细胞稳态，并改变不同动物设施中小鼠的T细胞反应。在此，我将讨论这些于2008年发表在《细胞宿主与微生物》杂志上的发现是如何产生的，以及它们如何有助于我们理解微生物群的免疫效应。
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Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8141-E8150. doi: 10.1073/pnas.1617460113. Epub 2016 Nov 23.
2
Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells.微生物与肠上皮细胞黏附诱导Th17细胞
Cell. 2015 Oct 8;163(2):367-80. doi: 10.1016/j.cell.2015.08.058. Epub 2015 Sep 24.
3
Induction of colonic regulatory T cells by indigenous Clostridium species.肠道共生梭菌诱导结肠调节性 T 细胞。
Science. 2011 Jan 21;331(6015):337-41. doi: 10.1126/science.1198469. Epub 2010 Dec 23.
4
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Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12204-9. doi: 10.1073/pnas.0909122107. Epub 2010 Jun 21.
5
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