Li Xuemei, Gao Min, Zhang Shengfa, Xu Huiwen, Zhou Huixuan, Wang Xiaohua, Qu Zhiyong, Guo Jing, Zhang Weijun, Tian Donghua
School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China; Clinics of Cadre, Department of Outpatient, General Hospital of the People's Liberation Army (301 Hospital), Beijing 100853, China.
School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China.
J Diabetes Res. 2017;2017:7589184. doi: 10.1155/2017/7589184. Epub 2017 Feb 9.
. To examine the association between Type D personality and HbA1c level and to explore the mediating role of medication adherence between them in patients with type 2 diabetes mellitus (T2DM). . 330 patients went on to complete a self-report measure of medication adherence and the HbA1c tests. Chi-square test, test, Ordinary Least Square Regression (OLS), and Recentered Influence Function Regression (RIF) were employed. . Patients with Type D personality had significantly higher HbA1c value ( < 0.01). When Type D personality was operationalized as a categorical variable, SI was associated with HbA1c ( < 0.01). When NA, SI, and their interaction term were entered into regression, all of them were no longer associated with HbA1c level ( > 0.1). On the other hand, when Type D personality was operationalized as a continuous variable, only SI trait was associated with HbA1c level ( < 0.01). When NA, SI, and NA × SI term together were entered into regression, only SI was not related to HbA1c level. Furthermore, medication adherence had a significant mediation effect between Type D personality and HbA1c, accounting for 54.43% of the total effect. . Type D personality was associated with HbA1c in direct and indirect ways, and medication adherence acted as a mediator role.
研究D型人格与糖化血红蛋白（HbA1c）水平之间的关联，并探讨药物依从性在2型糖尿病（T2DM）患者中二者之间的中介作用。330名患者继续完成了一份药物依从性的自我报告测量和HbA1c检测。采用卡方检验、检验、普通最小二乘法回归（OLS）和重新中心化影响函数回归（RIF）。D型人格患者的HbA1c值显著更高（<0.01）。当将D型人格作为分类变量时，消极情感（NA）与HbA1c相关（<0.01）。当将NA、消极情感（SI）及其交互项纳入回归时，它们均不再与HbA1c水平相关（>0.1）。另一方面，当将D型人格作为连续变量时，仅消极情感特质与HbA1c水平相关（<0.01）。当将NA、消极情感（SI）以及NA×SI项一起纳入回归时，只有消极情感（SI）与HbA1c水平无关。此外，药物依从性在D型人格和HbA1c之间具有显著的中介作用，占总效应的54.43%。D型人格通过直接和间接方式与HbA1c相关，且药物依从性起到中介作用。
