a Department of Chemistry , Banasthali Vidyapith , Banasthali , India.
b KIET School of Pharmacy , KIET Group of Institutions , Ghaziabad , India.
Crit Rev Anal Chem. 2017 Sep 3;47(5):405-417. doi: 10.1080/10408347.2017.1304200. Epub 2017 Mar 10.
Metformin is a widely prescribed oral anti-hyperglycemic agent used in the management of non-insulin dependent diabetes mellitus (NIDDM) or type II diabetes. This article accentuates various analytical methods viz. HPLC, HPTLC, spectrophotometric, electrochemical, capillary electrophoresis and LC-MS for the estimation of metformin in pharmaceutical formulations and in biological matrices.
二甲双胍是一种广泛应用于非胰岛素依赖型糖尿病（NIDDM）或 2 型糖尿病治疗的口服抗高血糖药物。本文强调了各种分析方法，如 HPLC、HPTLC、分光光度法、电化学、毛细管电泳和 LC-MS 用于药物制剂和生物基质中二甲双胍的测定。
