van Buul Amanda R, Kasteleyn Marise J, Chavannes Niels H, Taube Christian
a Department of Pulmonology , Leiden University Medical Center , Leiden , The Netherlands.
b Department of Public Health and Primary Care , Leiden University Medical Center , Leiden , The Netherlands.
Expert Rev Respir Med. 2017 Apr;11(4):311-322. doi: 10.1080/17476348.2017.1305894. Epub 2017 Mar 22.
Chronic obstructive pulmonary disease (COPD) patients experience the morning as the worst period of the day. Nevertheless, morning symptoms are not mentioned in COPD guidelines. Areas covered: Different topics on morning symptoms are covered in this review to underline their importance: occurrence, tools for assessment and therapies to limit morning symptoms. Expert commentary: Morning symptoms are common and have a negative influence on a patient's life. Pharmacotherapy seems to be effective in decreasing morning symptoms. A validated tool to assess morning symptoms is lacking. Therefore, more research should focus on assessing morning symptoms with a validated tool to further prove the effect of (pharmaco-) therapy. This will hopefully result in inclusion of morning symptoms in future guidelines.
慢性阻塞性肺疾病(COPD)患者觉得早晨是一天中状况最差的时段。然而,COPD指南中并未提及早晨症状。涵盖领域:本综述涵盖了关于早晨症状的不同主题,以强调其重要性:症状的发生、评估工具以及减轻早晨症状的疗法。专家评论:早晨症状很常见,且会对患者生活产生负面影响。药物治疗似乎对减轻早晨症状有效。目前缺乏用于评估早晨症状的有效工具。因此,更多研究应聚焦于使用有效工具评估早晨症状,以进一步证明(药物)治疗的效果。这有望促使早晨症状被纳入未来的指南中。