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与巨细胞动脉炎无关的多发性肌炎相关眼内炎症:三例报告。

Ocular Inflammation Associated with Polymyalgia Rheumatica without Concomitant Giant-Cell Arteritis: A Report of Three Cases.

机构信息

a Department of Ophthalmology , The University of Tokyo Hospital , Tokyo , Japan.

出版信息

Ocul Immunol Inflamm. 2018;26(5):779-782. doi: 10.1080/09273948.2017.1278776. Epub 2017 Feb 22.

Abstract

PURPOSE

We report three cases of ocular inflammation and polymyalgia rheumatica without concomitant giant-cell arteritis.

METHODS

Report of three cases.

RESULTS

Polymyalgia rheumatica onset was at a mean age of 66.7 years, and ocular inflammation, which developed 7-21 months later, was bilateral in all patients. Ocular inflammation presented as episcleritis, scleritis, or anterior uveitis, and it emerged during the tapering of low-dose prednisolone prescribed for polymyalgia rheumatica in all patients. Recurrence of ocular inflammation was observed in two patients.

CONCLUSIONS

Ocular inflammation associated with polymyalgia rheumatica was often bilateral and occurred during steroid tapering. Although this presentation is relatively uncommon, polymyalgia rheumatica should be considered in the differential diagnosis of older patients presenting with ocular inflammation, especially those with proximal myalgia and elevated inflammatory markers.

摘要

目的

我们报告三例伴发多发性肌痛性风湿症而无巨细胞动脉炎的眼部炎症病例。

方法

报告三例病例。

结果

多发性肌痛性风湿症的发病年龄平均为 66.7 岁,且在发病 7-21 个月后出现的眼部炎症在所有患者中均为双侧性。眼部炎症表现为表层巩膜炎、巩膜炎或前葡萄膜炎,且在所有患者中均发生于低剂量泼尼松龙减量治疗多发性肌痛性风湿症期间。两名患者出现了眼部炎症的复发。

结论

伴发多发性肌痛性风湿症的眼部炎症常为双侧性,并发生于类固醇减量期间。尽管这种表现相对不常见,但对于出现眼部炎症的老年患者,特别是那些伴有近端肌痛和炎症标志物升高的患者,应考虑多发性肌痛性风湿症的鉴别诊断。

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