Sharmin Sonia, Kypri Kypros, Khanam Masuma, Wadolowski Monika, Bruno Raimondo, Mattick Richard P
School of Medicine and Public Health, University of Newcastle, Newcastle, NSW 2308, Australia.
School of Health Science, University of Tasmania, Hobart, TAS 7005, Australia.
Int J Environ Res Public Health. 2017 Mar 9;14(3):287. doi: 10.3390/ijerph14030287.
Whether parental supply of alcohol affects the likelihood of later adolescent risky drinking remains unclear. We conducted a systematic review and meta-analysis to synthesize findings from longitudinal studies investigating this association. We searched eight electronic databases up to 10 September 2016 for relevant terms and included only original English language peer-reviewed journal articles with a prospective design. Two reviewers independently screened articles, extracted data and assessed risk of bias. Seven articles met inclusion criteria, six of which used analytic methods allowing for meta-analysis. In all seven studies, the follow-up period was ≥12 months and attrition ranged from 3% to 15%. Parental supply of alcohol was associated with subsequent risky drinking (odds ratio = 2.00, 95% confidence interval = 1.72, 2.32); however, there was substantial risk of confounding bias and publication bias. In all studies, measurement of exposure was problematic given the lack of distinction between parental supply of sips of alcohol versus whole drinks. In conclusion, parental supply of alcohol in childhood is associated with an increased likelihood of risky drinking later in adolescence. However, methodological limitations preclude a causal inference. More robust longitudinal studies are needed, with particular attention to distinguishing sips from whole drinks, measurement of likely confounders, and multivariable adjustment.
父母提供酒精是否会影响青少年后期危险饮酒的可能性仍不清楚。我们进行了一项系统综述和荟萃分析，以综合调查这种关联的纵向研究结果。我们在截至2016年9月10日的八个电子数据库中搜索相关术语，仅纳入具有前瞻性设计的英文原创同行评审期刊文章。两名评审员独立筛选文章、提取数据并评估偏倚风险。七篇文章符合纳入标准，其中六篇使用了允许进行荟萃分析的分析方法。在所有七项研究中，随访期≥12个月，失访率在3%至15%之间。父母提供酒精与随后的危险饮酒有关（比值比=2.00，95%置信区间=1.72，2.32）；然而，存在相当大的混杂偏倚和发表偏倚风险。在所有研究中，由于缺乏对父母提供小酌与整杯酒之间的区分，暴露测量存在问题。总之，童年时期父母提供酒精与青少年后期危险饮酒的可能性增加有关。然而，方法学上的局限性妨碍了因果推断。需要更有力的纵向研究，尤其要注意区分小酌与整杯酒、测量可能的混杂因素以及多变量调整。
