Akhlaghi Parisa, Ebrahimi-Khankook Atiyeh, Vejdani-Noghreiyan Alireza
Department of Medical Physics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Physics Department, Faculty of Sciences, University of Neyshabur, Neyshabur, Iran.
Radiat Environ Biophys. 2017 May;56(2):177-186. doi: 10.1007/s00411-017-0686-5. Epub 2017 Mar 10.
In head computed tomography, radiation upon the eye lens (as an organ with high radiosensitivity) may cause lenticular opacity and cataracts. Therefore, quantitative dose assessment due to exposure of the eye lens and surrounding tissue is a matter of concern. For this purpose, an accurate eye model with realistic geometry and shape, in which different eye substructures are considered, is needed. To calculate the absorbed radiation dose of visual organs during head computed tomography scans, in this study, an existing sophisticated eye model was inserted at the related location in the head of the reference adult male phantom recommended by the International Commission on Radiological Protection (ICRP). Then absorbed doses and distributions of energy deposition in different parts of this eye model were calculated and compared with those based on a previous simple eye model. All calculations were done using the Monte Carlo code MCNP4C for tube voltages of 80, 100, 120 and 140 kVp. In spite of the similarity of total dose to the eye lens for both eye models, the dose delivered to the sensitive zone, which plays an important role in the induction of cataracts, was on average 3% higher for the sophisticated model as compared to the simple model. By increasing the tube voltage, differences between the total dose to the eye lens between the two phantoms decrease to 1%. Due to this level of agreement, use of the sophisticated eye model for patient dosimetry is not necessary. However, it still helps for an estimation of doses received by different eye substructures separately.
在头部计算机断层扫描中,辐射作用于晶状体(作为一种对辐射高度敏感的器官)可能会导致晶状体混浊和白内障。因此,对晶状体及周围组织暴露所致的剂量进行定量评估是一个值得关注的问题。为此,需要一个具有真实几何形状和形态的精确眼部模型,其中要考虑到不同的眼部亚结构。为了计算头部计算机断层扫描期间视觉器官的吸收辐射剂量,在本研究中,将一个现有的精密眼部模型插入到国际放射防护委员会(ICRP)推荐的参考成年男性体模头部的相关位置。然后计算该眼部模型不同部位的吸收剂量和能量沉积分布,并与基于先前简单眼部模型的结果进行比较。所有计算均使用蒙特卡罗代码MCNP4C,管电压分别为80、100、120和140 kVp。尽管两种眼部模型对晶状体的总剂量相似,但与简单模型相比,精密模型传递到在白内障诱发中起重要作用的敏感区的剂量平均高出3%。随着管电压的增加,两个体模对晶状体的总剂量差异降至1%。由于这种一致性水平,使用精密眼部模型进行患者剂量测定并非必要。然而,它仍然有助于分别估算不同眼部亚结构所接受的剂量。