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黄芩根中五种生物活性成分的含量分布模式。

Distribution patterns of the contents of five biologically activate ingredients in the root of Scutellaria baicalensis.

作者信息

Liu Rong-Xiu, Song Guo-Hu, Wu Pei-Gen, Zhang Xue-Wen, Hu Hui-Juan, Liu Jia, Miao Xiao-Su, Hou Zhi-Yan, Wang Wen-Quan, Wei Sheng-Li

机构信息

School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China.

Chengde Pharmaceutical Co., Ltd Affiliated to China National Group Corp. of Traditional & Herbal Medicine, Chengde 067000, China.

出版信息

Chin J Nat Med. 2017 Feb;15(2):152-160. doi: 10.1016/S1875-5364(17)30030-4.

DOI:10.1016/S1875-5364(17)30030-4
PMID:28284428
Abstract

As an important herbaceous plant, Scutellaria baicalensis Georgi (Chinese skullcap) is geographically widespread and commonly used throughout the world. In the Chinese medicine market, S. baicalensis has been divided into two primary types, "Ku Qin" (WXR) and "Tiao Qin" (TST). Moreover, TST is also divided into different grades according to the diameter of roots. To explore the distribution patterns of the contents of five biologically activate ingredients (FBAI), we used six-year-old cultivated S. baicalensis and analyzed its growth characteristics as well as the quality difference among different types and diameters in roots. Throughout the entire root, we discovered that contents of the FBAI all initially increased and subsequently decreased from the top to the bottom of the roots. The baicalin content of WXR was less than that of TST. On the contrary, the contents of baicalein, wogonin, and oroxylin A in WXR were up to about two times higher than that in TST. We also found that the 0 to 40 cm part of the S. baicalensis root possessed about 87% of the root biomass and about 92% of the contents of the active ingredients.

摘要

作为一种重要的草本植物,黄芩在世界各地广泛分布且被普遍使用。在中国医药市场,黄芩被分为两种主要类型,“枯芩”(WXR)和“条芩”(TST)。此外,条芩还根据根的直径分为不同等级。为了探究五种生物活性成分(FBAI)含量的分布模式,我们使用了六年生栽培黄芩,分析了其生长特性以及不同类型和根直径之间的质量差异。在整个根中,我们发现FBAI的含量从根的顶部到底部均先增加后减少。枯芩的黄芩苷含量低于条芩。相反,枯芩中黄芩素、汉黄芩素和木犀草素A的含量比条芩中高出约两倍。我们还发现,黄芩根0至40厘米部分占根生物量的约87%以及活性成分含量的约92%。

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