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孕期急性髓系白血病经柔红霉素治疗后的正常婴儿。

Normal infant after treatment of acute myeloid leukaemia in pregnancy with daunorubicin.

作者信息

Lowenthal R M, Marsden K A, Newman N M, Baikie M J, Campbell S N

出版信息

Aust N Z J Med. 1978 Aug;8(4):431-2. doi: 10.1111/j.1445-5994.1978.tb04918.x.

DOI:10.1111/j.1445-5994.1978.tb04918.x
PMID:282860
Abstract

Daunorubicin, thioguanine and cytosine arabinoside were administered from the 17th to 34th weeks of pregnancy in a 23-year-old patient with acute myeloid leukaemia. The patient went into remission of her leukaemia, and a normal male infant was born after labour was induced in the 40th week. This experience supports the view that modern regimens of anti-leukaemic drugs may be administered during the second and third trimesters of pregnancy without harmful effects on the foetus.

摘要

一名23岁的急性髓系白血病患者在怀孕第17至34周期间接受了柔红霉素、硫鸟嘌呤和阿糖胞苷的治疗。患者的白血病进入缓解期,在第40周引产分娩后,一名正常男婴出生。这一经验支持了这样一种观点,即在妊娠中期和晚期可以使用现代抗白血病药物方案,而不会对胎儿产生有害影响。

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