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The Wag31 protein interacts with AccA3 and coordinates cell wall lipid permeability and lipophilic drug resistance in Mycobacterium smegmatis.Wag31 蛋白与 AccA3 相互作用,协调分枝杆菌细胞壁脂质通透性和疏水性药物耐药性。
Biochem Biophys Res Commun. 2014 Jun 6;448(3):255-60. doi: 10.1016/j.bbrc.2014.04.116. Epub 2014 Apr 30.
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A case of Mycobacterium goodii prosthetic valve endocarditis in a non-immunocompromised patient: use of 16S rDNA analysis for rapid diagnosis.16S rDNA 分析快速诊断非免疫抑制患者的固着型心内膜炎
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Antimicrobial susceptibility testing, drug resistance mechanisms, and therapy of infections with nontuberculous mycobacteria.非结核分枝杆菌感染的抗菌药物敏感性试验、耐药机制及治疗。
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Pediatr Infect Dis J. 2011 May;30(5):447-8. doi: 10.1097/INF.0b013e3182024c1c.
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Conn Med. 2008 Feb;72(2):75-7.
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一种新出现的医院病原体:病例报告及文献综述

An Emerging Nosocomial Pathogen: A Case Report and Review of the Literature.

作者信息

Salas Natalie Mariam, Klein Nicole

机构信息

University of New Mexico; and †Division of Infectious Disease, Department of Internal Medicine, Raymond G. Murphy VA Medical Center, Albuquerque, NM.

出版信息

Infect Dis Clin Pract (Baltim Md). 2017 Mar;25(2):62-65. doi: 10.1097/IPC.0000000000000428. Epub 2016 Aug 9.

DOI:10.1097/IPC.0000000000000428
PMID:28286403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5331875/
Abstract

, a rapidly growing nontuberculous mycobacterium, is an emerging pathogen in nosocomial infections. Its inherent resistance patterns make it a challenging organism to treat, and delays in identification can lead to poor outcomes. We present a case of cardiac device pocket infection with , complicated by both antibiotic resistance and drug reactions that highlight the challenges faced by clinicians trying to eradicate these infections. We also present a brief review of the English literature surrounding this disease, including a table of all reported cases of infections and their outcomes to act as guide for clinicians formulating treatment plans for these infections. A clear understanding of diagnostic methods and treatment caveats is essential to curing infections caused by these organisms.

摘要

作为一种快速生长的非结核分枝杆菌,是医院感染中一种新出现的病原体。其固有的耐药模式使其成为一种难以治疗的微生物,而鉴定延迟可能导致不良后果。我们报告一例心脏装置囊袋感染病例,该病例合并抗生素耐药和药物反应,凸显了临床医生在试图根除这些感染时面临的挑战。我们还简要回顾了围绕该疾病的英文文献,包括所有已报告的感染病例及其结果的表格,以指导临床医生制定这些感染的治疗方案。清楚了解诊断方法和治疗注意事项对于治愈由这些微生物引起的感染至关重要。