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复发性腹泻的治疗

Treatment of Recurrent Diarrhea.

作者信息

Huebner Elizabeth S, Surawicz Christina M

机构信息

Dr. Huebner is a Fellow in the Division of Gastroenterology at the University of Washington School of Medicine in Seattle, where Dr. Surawicz is Professor of Medicine, Section Chief in Gastroenterology at the Harborview Medical Center, and Assistant Dean for Faculty Development.

出版信息

Gastroenterol Hepatol (N Y). 2006 Mar;2(3):203-208.

Abstract

Treatment of recurrent -associated diarrhea can be challenging. Once patients develop recurrent disease, further episodes are common and can continue for months or even a year or more. Treatment begins with a repeat standard 10-day course of antibiotics, followed by tapering and/or pulsing of the antibiotic dose. Probiotics can also be useful, particularly the nonpathogenic yeast . Stool reconstitution via fecal enemas, colonoscopy, and nasogastric tubes have been performed to restore normal colonic flora. Additional approaches under investigation, such as vaccination against , show encouraging preliminary results.

摘要

复发性相关腹泻的治疗可能具有挑战性。一旦患者出现复发性疾病,进一步发作很常见,可能持续数月甚至一年或更长时间。治疗首先是重复标准的10天抗生素疗程,然后逐渐减少和/或脉冲式给予抗生素剂量。益生菌也可能有用,特别是非致病性酵母。已通过粪便灌肠、结肠镜检查和鼻胃管进行粪便重建以恢复正常结肠菌群。正在研究的其他方法,如针对……的疫苗接种,显示出令人鼓舞的初步结果。

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