• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

心脏手术患者术前抗高血压药物与术后心房颤动的关系：一项荟萃分析

Preoperative Antihypertensive Medication in Relation to Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: A Meta-Analysis.

作者信息

Zhou Ai-Guo, Wang Xian-Xue, Pan Dao-Bo, Chen An-Ji, Zhang Xiong-Fei, Deng Hui-Wei

机构信息

Department of Anesthesiology of the First People's Hospital of Changde City, Changde, Hunan, China.

出版信息

Biomed Res Int. 2017;2017:1203538. doi: 10.1155/2017/1203538. Epub 2017 Feb 13.

DOI:10.1155/2017/1203538
PMID:28286753
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5327763/
Abstract

. We undertake a systematic review and meta-analysis to evaluate the effect of preoperative hypertension and preoperative antihypertensive medication to postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery. . We searched PubMed, Embase, and Cochrane Library (from inception to March 2016) for eligible studies. The outcomes were the effects of preoperative hypertension, preoperative calcium antagonists regimen, preoperative ACE inhibitors regimen, and preoperative beta blocking agents regimen with POAF. We calculated pooled risk ratios (OR) and 95% CIs using random- or fixed-effects models. . Twenty-five trials involving 130087 patients were listed. Meta-analysis showed that the number of preoperative hypertension patients in POAF group was significantly higher ( < 0.05), while we found that there are no significant differences between two groups in Asia patients by subgroup analysis, which is in contrast to other outcomes. Compared with the Non-POAF group, the number of patients who used calcium antagonists and ACE inhibitors preoperatively in POAF group was significantly higher ( < 0.05). And we found that there were no significant differences between two groups of preoperative beta blocking agents used ( = 0.08). . Preoperative hypertension and preoperative antihypertensive medication in patients undergoing cardiac operations seem to be associated with higher risk of POAF.

摘要

我们进行了一项系统评价和荟萃分析，以评估心脏手术患者术前高血压和术前抗高血压药物对术后心房颤动（POAF）的影响。我们检索了PubMed、Embase和Cochrane图书馆（从创刊至2016年3月）以查找符合条件的研究。结局指标为术前高血压、术前钙拮抗剂方案、术前血管紧张素转换酶抑制剂方案和术前β受体阻滞剂方案对POAF的影响。我们使用随机或固定效应模型计算合并风险比（OR）和95%置信区间。列出了涉及130087例患者的25项试验。荟萃分析显示，POAF组术前高血压患者数量显著更高（<0.05），而亚组分析发现亚洲患者两组之间无显著差异，这与其他结局相反。与非POAF组相比，POAF组术前使用钙拮抗剂和血管紧张素转换酶抑制剂的患者数量显著更高（<0.05）。并且我们发现两组术前使用β受体阻滞剂无显著差异（=0.08）。心脏手术患者术前高血压和术前抗高血压药物似乎与POAF风险较高相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/9eab1a363689/BMRI2017-1203538.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/99703384cd3e/BMRI2017-1203538.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/57569d4c554f/BMRI2017-1203538.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/7bfa2fe5ad09/BMRI2017-1203538.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/5be428c1726d/BMRI2017-1203538.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/13e0a8c469cb/BMRI2017-1203538.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/9eab1a363689/BMRI2017-1203538.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/99703384cd3e/BMRI2017-1203538.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/57569d4c554f/BMRI2017-1203538.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/7bfa2fe5ad09/BMRI2017-1203538.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/5be428c1726d/BMRI2017-1203538.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/13e0a8c469cb/BMRI2017-1203538.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/5327763/9eab1a363689/BMRI2017-1203538.006.jpg

相似文献

1
Preoperative Antihypertensive Medication in Relation to Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: A Meta-Analysis.心脏手术患者术前抗高血压药物与术后心房颤动的关系：一项荟萃分析
Biomed Res Int. 2017;2017:1203538. doi: 10.1155/2017/1203538. Epub 2017 Feb 13.
2
Beta-blockers for hypertension.用于治疗高血压的β受体阻滞剂。
Cochrane Database Syst Rev. 2007 Jan 24(1):CD002003. doi: 10.1002/14651858.CD002003.pub2.
3
Beta-blockers for hypertension.用于治疗高血压的β受体阻滞剂。
Cochrane Database Syst Rev. 2017 Jan 20;1(1):CD002003. doi: 10.1002/14651858.CD002003.pub5.
4
First-line drugs for hypertension.高血压一线用药。
Cochrane Database Syst Rev. 2018 Apr 18;4(4):CD001841. doi: 10.1002/14651858.CD001841.pub3.
5
Intravenous magnesium sulphate and sotalol for prevention of atrial fibrillation after coronary artery bypass surgery: a systematic review and economic evaluation.静脉注射硫酸镁和索他洛尔预防冠状动脉搭桥术后房颤：系统评价与经济学评估
Health Technol Assess. 2008 Jun;12(28):iii-iv, ix-95. doi: 10.3310/hta12280.
6
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.成人全身麻醉后预防术后恶心呕吐的药物：网状Meta分析
Cochrane Database Syst Rev. 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2.
7
Preoperative Use of Oral Beta-Adrenergic Blocking Agents and the Incidence of New-Onset Atrial Fibrillation After Cardiac Surgery. A Systematic Review and Meta-Analysis.口服β-肾上腺素能阻滞剂的术前使用与心脏手术后新发房颤的发生率。一项系统评价和荟萃分析。
Heart Lung Circ. 2018 Mar;27(3):310-321. doi: 10.1016/j.hlc.2017.08.026. Epub 2017 Oct 19.
8
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.系统性药理学治疗慢性斑块状银屑病：网络荟萃分析。
Cochrane Database Syst Rev. 2021 Apr 19;4(4):CD011535. doi: 10.1002/14651858.CD011535.pub4.
9
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.慢性斑块状银屑病的全身药理学治疗：一项网状荟萃分析。
Cochrane Database Syst Rev. 2017 Dec 22;12(12):CD011535. doi: 10.1002/14651858.CD011535.pub2.
10
Systemic treatments for metastatic cutaneous melanoma.转移性皮肤黑色素瘤的全身治疗
Cochrane Database Syst Rev. 2018 Feb 6;2(2):CD011123. doi: 10.1002/14651858.CD011123.pub2.

引用本文的文献

1
Calcium channels in anesthesia management: A molecular and clinical review.麻醉管理中的钙通道：分子与临床综述
Mol Pain. 2025 Jan-Dec;21:17448069251343417. doi: 10.1177/17448069251343417. Epub 2025 May 10.
2
Effectiveness of Anti-Inflammatory Agents to Prevent Atrial Fibrillation After Cardiac Surgery: A Systematic Review and Network Meta-Analysis.抗炎药物预防心脏手术后房颤的有效性：一项系统评价和网状Meta分析
CJC Open. 2024 Oct 29;7(1):35-45. doi: 10.1016/j.cjco.2024.10.008. eCollection 2025 Jan.
3
Risk and protective factors for atrial fibrillation after cardiac surgery and valvular interventions: an umbrella review of meta-analyses.

本文引用的文献

1
Postoperative atrial fibrillation in non-cardiac and cardiac surgery: an overview.非心脏和心脏手术中的术后心房颤动：概述。
J Thromb Haemost. 2015 Jun;13 Suppl 1:S304-12. doi: 10.1111/jth.12974.
2
Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery.在心脏手术中，炎症、氧化应激与术后心房颤动。
Pharmacol Ther. 2015 Oct;154:13-20. doi: 10.1016/j.pharmthera.2015.06.009. Epub 2015 Jun 24.
3
Transient post-operative atrial fibrillation predicts short and long term adverse events following CABG.
心脏手术后和瓣膜介入后心房颤动的风险和保护因素：荟萃分析的伞式综述。
Open Heart. 2022 Sep;9(2). doi: 10.1136/openhrt-2022-002074.
4
Programmed intermittent epidural bolus in parturients: A meta-analysis of randomized controlled trials.产妇程控间歇性硬膜外推注：随机对照试验的荟萃分析。
Medicine (Baltimore). 2022 Feb 4;101(5):e28742. doi: 10.1097/MD.0000000000028742.
5
Oral Pregabalin in Cardiac Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.心脏手术中口服普瑞巴林：随机对照试验的系统评价和荟萃分析。
Biomed Res Int. 2021 Mar 3;2021:8835891. doi: 10.1155/2021/8835891. eCollection 2021.
术后短暂性房颤可预测冠状动脉旁路移植术后的短期和长期不良事件。
Cardiovasc Diagn Ther. 2014 Oct;4(5):365-72. doi: 10.3978/j.issn.2223-3652.2014.09.02.
4
Postoperative atrial fibrillation significantly increases mortality, hospital readmission, and hospital costs.术后房颤会显著增加死亡率、住院再入院率及住院费用。
Ann Thorac Surg. 2014 Aug;98(2):527-33; discussion 533. doi: 10.1016/j.athoracsur.2014.03.039.
5
Advanced age and incidence of atrial fibrillation in the postoperative period of aortic valve replacement.高龄与主动脉瓣置换术后房颤的发生率
Rev Bras Cir Cardiovasc. 2014 Jan-Mar;29(1):45-50. doi: 10.5935/1678-9741.20140010.
6
Bedside tool for predicting the risk of postoperative atrial fibrillation after cardiac surgery: the POAF score.预测心脏手术后发生术后心房颤动风险的床边工具：POAF评分
J Am Heart Assoc. 2014 Mar 24;3(2):e000752. doi: 10.1161/JAHA.113.000752.
7
New-onset atrial fibrillation predicts long-term newly developed atrial fibrillation after coronary artery bypass graft.新发心房颤动可预测冠状动脉旁路移植术后长期新发心房颤动。
Am Heart J. 2014 Apr;167(4):593-600.e1. doi: 10.1016/j.ahj.2013.12.010. Epub 2014 Jan 4.
8
Perioperative stroke: risk assessment, prevention and treatment.围手术期卒中：风险评估、预防与治疗
Curr Treat Options Cardiovasc Med. 2014 Feb;16(2):282. doi: 10.1007/s11936-013-0282-1.
9
What do we actually know about the relationship between arterial hypertension and atrial fibrillation?关于动脉高血压与心房颤动之间的关系，我们实际上了解多少？
Blood Press. 2014 Apr;23(2):81-8. doi: 10.3109/08037051.2013.814234. Epub 2013 Jul 29.
10
Predictive value of total atrial conduction time measured with tissue Doppler imaging for postoperative atrial fibrillation after coronary artery bypass surgery.组织多普勒成像测量的全心房传导时间对冠状动脉搭桥术后心房颤动的预测价值。
J Interv Card Electrophysiol. 2013 Jun;37(1):27-33. doi: 10.1007/s10840-012-9756-4. Epub 2012 Dec 13.