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多聚体的诊疗价值：从神经降压素受体配体及其他靶向载体的三聚化中获得的经验教训。

Theranostic Value of Multimers: Lessons Learned from Trimerization of Neurotensin Receptor Ligands and Other Targeting Vectors.

作者信息

Maschauer Simone, Einsiedel Jürgen, Reich Dominik, Hübner Harald, Gmeiner Peter, Wester Hans-Jürgen, Prante Olaf, Notni Johannes

机构信息

Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054 Erlangen, Germany.

Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schuhstraße 19, 91052 Erlangen, Germany.

出版信息

Pharmaceuticals (Basel). 2017 Mar 10;10(1):29. doi: 10.3390/ph10010029.

DOI:10.3390/ph10010029
PMID:28287433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5374433/
Abstract

Neurotensin receptor 1 (NTS1) is overexpressed on a variety of cancer entities; for example, prostate cancer, ductal pancreatic adenocarcinoma, and breast cancer. Therefore, it represents an interesting target for the diagnosis of these cancers types by positron emission tomography (PET) [...].

摘要

神经降压素受体1（NTS1）在多种癌症实体中过度表达；例如，前列腺癌、胰腺导管腺癌和乳腺癌。因此，它是通过正电子发射断层扫描（PET）诊断这些癌症类型的一个有趣靶点[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/852aa65ca9f7/pharmaceuticals-10-00029-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/91d6438657da/pharmaceuticals-10-00029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/10e39826863f/pharmaceuticals-10-00029-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/7278d9aa8357/pharmaceuticals-10-00029-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/cee837cb092e/pharmaceuticals-10-00029-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/852aa65ca9f7/pharmaceuticals-10-00029-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/91d6438657da/pharmaceuticals-10-00029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/10e39826863f/pharmaceuticals-10-00029-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/7278d9aa8357/pharmaceuticals-10-00029-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/cee837cb092e/pharmaceuticals-10-00029-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8376/5374433/852aa65ca9f7/pharmaceuticals-10-00029-g005.jpg

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