多聚体的诊疗价值：从神经降压素受体配体及其他靶向载体的三聚化中获得的经验教训。

Theranostic Value of Multimers: Lessons Learned from Trimerization of Neurotensin Receptor Ligands and Other Targeting Vectors.

作者信息

Maschauer Simone, Einsiedel Jürgen, Reich Dominik, Hübner Harald, Gmeiner Peter, Wester Hans-Jürgen, Prante Olaf, Notni Johannes

机构信息

Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054 Erlangen, Germany.

Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schuhstraße 19, 91052 Erlangen, Germany.

出版信息

Pharmaceuticals (Basel). 2017 Mar 10;10(1):29. doi: 10.3390/ph10010029.

Neurotensin receptor 1 (NTS1) is overexpressed on a variety of cancer entities; for example, prostate cancer, ductal pancreatic adenocarcinoma, and breast cancer. Therefore, it represents an interesting target for the diagnosis of these cancers types by positron emission tomography (PET) [...].