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多种气体递质在血管内介导异细胞通讯中不断演变的作用

The Evolving Role of Diverse Gaseous Transmitters Mediating Heterocellular Communication Within the Vasculature.

作者信息

Keller Alexander S, Isakson Brant E

机构信息

1 Department of Pharmacology, University of Virginia School of Medicine , Charlottesville, Virginia.

3 Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine , Charlottesville, Virginia.

出版信息

Antioxid Redox Signal. 2017 Jun 1;26(16):881-885. doi: 10.1089/ars.2017.7059. Epub 2017 Apr 14.

Abstract

Heterocellular communication between different cell types of the vasculature, both within the blood vessel wall and cells interacting with the blood vessel wall, is absolutely vital and must be tightly regulated. In this Forum, the role of four different gaseous transmitters [nitric oxide [NO], carbon monoxide (CO), hydrogen sulfide (HS), and superoxide (O)] is examined by four different research groups in detail, with two original articles and two reviews of the literature. In this editorial, we discuss how each of them may contribute their own component to heterocellular signaling in the vasculature. Antioxid. Redox Signal. 26, 881-885.

摘要

血管不同细胞类型之间的异细胞通讯,无论是在血管壁内还是与血管壁相互作用的细胞之间,都至关重要且必须受到严格调控。在本论坛中,四个不同的研究小组详细研究了四种不同的气体递质[一氧化氮(NO)、一氧化碳(CO)、硫化氢(HS)和超氧阴离子(O)]的作用,包括两篇原创文章和两篇文献综述。在这篇社论中,我们讨论了它们各自如何对血管中的异细胞信号传导发挥作用。《抗氧化与氧化还原信号》26卷,881 - 885页。

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