• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Response by Methawasin and Granzier to Letter Regarding Article, "Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function in a Mouse Model of Heart Failure With Preserved Ejection Fraction".

作者信息

Methawasin Mei, Granzier Henk

机构信息

From Department of Cellular and Molecular Medicine, College of Medicine, University of Arizona, Tucson.

出版信息

Circulation. 2017 Mar 14;135(11):e681-e682. doi: 10.1161/CIRCULATIONAHA.117.026955.

DOI:10.1161/CIRCULATIONAHA.117.026955
PMID:28289010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5401660/
Abstract
摘要

相似文献

1
Response by Methawasin and Granzier to Letter Regarding Article, "Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function in a Mouse Model of Heart Failure With Preserved Ejection Fraction".Methawasin和格兰齐尔对关于文章《通过RNA结合基序20（RBM20）抑制实验性增加肌联蛋白的顺应性可改善射血分数保留的心力衰竭小鼠模型的舒张功能》的信件的回复
Circulation. 2017 Mar 14;135(11):e681-e682. doi: 10.1161/CIRCULATIONAHA.117.026955.
2
Letter by Lewis and Miller Regarding Article, "Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function in a Mouse Model of Heart Failure With Preserved Ejection Fraction".刘易斯和米勒就文章《通过RNA结合基序20（RBM20）抑制实验性增加肌联蛋白的顺应性可改善射血分数保留的心力衰竭小鼠模型的舒张功能》所写的信函
Circulation. 2017 Mar 14;135(11):e679-e680. doi: 10.1161/CIRCULATIONAHA.116.025995.
3
Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction.通过抑制RNA结合基序20（RBM20）实验性增加肌联蛋白的顺应性可改善射血分数保留的心力衰竭小鼠模型的舒张功能。
Circulation. 2016 Oct 11;134(15):1085-1099. doi: 10.1161/CIRCULATIONAHA.116.023003. Epub 2016 Sep 14.
4
Alternative Splicing of Titin Restores Diastolic Function in an HFpEF-Like Genetic Murine Model (TtnΔIAjxn).肌联蛋白的可变剪接可恢复类似射血分数保留型心力衰竭遗传小鼠模型（TtnΔIAjxn）的舒张功能。
Circ Res. 2016 Sep 2;119(6):764-72. doi: 10.1161/CIRCRESAHA.116.308904. Epub 2016 Jul 28.
5
Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole.在一种新型小鼠模型中实验性增加原肌球蛋白顺应性可减弱 Frank-Starling 机制，但对舒张期有有益影响。
Circulation. 2014 May 13;129(19):1924-36. doi: 10.1161/CIRCULATIONAHA.113.005610. Epub 2014 Mar 5.
6
Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.降低RBM20活性可改善舒张功能障碍和心脏萎缩。
J Mol Med (Berl). 2016 Dec;94(12):1349-1358. doi: 10.1007/s00109-016-1483-3. Epub 2016 Nov 26.
7
Myocardial titin hypophosphorylation importantly contributes to heart failure with preserved ejection fraction in a rat metabolic risk model.肌联蛋白低磷酸化在代谢风险大鼠模型心力衰竭伴射血分数保留中起着重要作用。
Circ Heart Fail. 2013 Nov;6(6):1239-49. doi: 10.1161/CIRCHEARTFAILURE.113.000539. Epub 2013 Sep 6.
8
Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue.在小鼠心力衰竭模型和人类工程心脏组织中，对RBM20进行治疗性抑制可改善舒张功能。
Sci Transl Med. 2021 Dec;13(622):eabe8952. doi: 10.1126/scitranslmed.abe8952. Epub 2021 Dec 1.
9
Response by Methawasin and Granzier to Letter Regarding Article, "Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction".梅塔瓦辛和格兰齐尔对关于“舒张功能障碍小鼠模型中磷酸二酯酶9a抑制作用”一文的信件的回应
Circ Heart Fail. 2021 Jan;14(1):e007755. doi: 10.1161/CIRCHEARTFAILURE.120.007755. Epub 2021 Jan 19.
10
Dual Endothelin-A/Endothelin-B Receptor Blockade and Cardiac Remodeling in Heart Failure With Preserved Ejection Fraction.双重内皮素-A/内皮素-B受体阻断与射血分数保留的心力衰竭中的心脏重塑
Circ Heart Fail. 2016 Nov;9(11). doi: 10.1161/CIRCHEARTFAILURE.116.003381.

本文引用的文献

1
Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.降低RBM20活性可改善舒张功能障碍和心脏萎缩。
J Mol Med (Berl). 2016 Dec;94(12):1349-1358. doi: 10.1007/s00109-016-1483-3. Epub 2016 Nov 26.
2
Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction.通过抑制RNA结合基序20（RBM20）实验性增加肌联蛋白的顺应性可改善射血分数保留的心力衰竭小鼠模型的舒张功能。
Circulation. 2016 Oct 11;134(15):1085-1099. doi: 10.1161/CIRCULATIONAHA.116.023003. Epub 2016 Sep 14.
3
Therapeutic targets in heart failure: refocusing on the myocardial interstitium.心力衰竭的治疗靶点：重新聚焦于心肌间质。
J Am Coll Cardiol. 2014 Jun 3;63(21):2188-98. doi: 10.1016/j.jacc.2014.01.068. Epub 2014 Mar 19.
4
Biomarkers of diastolic dysfunction and myocardial fibrosis: application to heart failure with a preserved ejection fraction.舒张功能障碍和心肌纤维化的生物标志物：在心衰伴射血分数保留中的应用。
J Cardiovasc Transl Res. 2013 Aug;6(4):501-15. doi: 10.1007/s12265-013-9472-1. Epub 2013 May 29.
5
Titin: physiological function and role in cardiomyopathy and failure.肌联蛋白：生理功能及其在心肌病和心力衰竭中的作用
Heart Fail Rev. 2005 Sep;10(3):211-23. doi: 10.1007/s10741-005-5251-7.