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[乳腺癌活检与预后的关系]

[Relationship between biopsy and prognosis of breast cancer].

作者信息

Fujimori M, Senga O, Terai N, Miyagawa M, Iida F, Tsuchiya S, Koike Y

机构信息

Second Department of Surgery, Shinshu University School of Medicine Matsumoto, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1987 Nov;88(11):1619-23.

PMID:2828910
Abstract

Clinical data from 131 patients who underwent primary radical operation for breast cancer at the Second Department of Surgery, Shinshu University Hospital during five-years from January 1976 to the end of December 1980 were analyzed to investigate for the relationship between biopsy and prognosis. The incisional biopsy group had a significant higher recurrence rate as compared with the no biopsy group, cytology group and the cancer negative group after excisional biopsy. Although the puncture aspiration cytology group did not show significant difference in recurrence rate, an any more than 3 weeks of interval between puncture aspiration cytology and radical surgery associated with a significant high recurrence rate. This suggests that the interval also exerts an unfavorable influence upon prognosis. Puncture aspiration cytology was recognized to be apt to result in distant metastasis than any other biopsy methods and also it is tended to have a higher recurrence rate in scirrhous and mucinous carcinoma of the breast.

摘要

对1976年1月至1980年12月底五年间在信州大学医院第二外科接受乳腺癌一期根治手术的131例患者的临床资料进行分析,以研究活检与预后的关系。与未活检组、细胞学检查组和切除活检后癌阴性组相比,切开活检组的复发率显著更高。虽然穿刺抽吸细胞学检查组的复发率没有显著差异,但穿刺抽吸细胞学检查与根治手术之间间隔超过3周会导致复发率显著升高。这表明该间隔时间也对预后产生不利影响。与其他活检方法相比,穿刺抽吸细胞学检查更容易导致远处转移,并且在乳腺硬癌和黏液癌中复发率也往往更高。

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