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创伤性凝血病的病理生理学：具有纤维蛋白溶解表型的弥散性血管内凝血。

Pathophysiology of trauma-induced coagulopathy: disseminated intravascular coagulation with the fibrinolytic phenotype.

作者信息

Hayakawa Mineji

机构信息

Emergency and Critical Care Center, Hokkaido University Hospital, N14W5 Kita-ku, Sapporo, 060-8648 Japan.

出版信息

J Intensive Care. 2017 Jan 31;5:14. doi: 10.1186/s40560-016-0200-1. eCollection 2017.

DOI:10.1186/s40560-016-0200-1
PMID:28289544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5282695/
Abstract

In severe trauma patients, coagulopathy is frequently observed in the acute phase of trauma. Trauma-induced coagulopathy is coagulopathy caused by the trauma itself. The pathophysiology of trauma-induced coagulopathy consists of coagulation activation, hyperfibrino(geno)lysis, and consumption coagulopathy. These pathophysiological mechanisms are the characteristics to DIC with the fibrinolytic phenotype.

摘要

在严重创伤患者中，创伤急性期常出现凝血病。创伤性凝血病是由创伤本身引起的凝血病。创伤性凝血病的病理生理学包括凝血激活、高纤维蛋白（原）溶解和消耗性凝血病。这些病理生理机制是具有纤溶表型的弥散性血管内凝血的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fa2/5282695/d20f4a54b2e6/40560_2016_200_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fa2/5282695/1f0cdd3c8636/40560_2016_200_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fa2/5282695/45a360ea5fb2/40560_2016_200_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fa2/5282695/d20f4a54b2e6/40560_2016_200_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fa2/5282695/1f0cdd3c8636/40560_2016_200_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fa2/5282695/45a360ea5fb2/40560_2016_200_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fa2/5282695/d20f4a54b2e6/40560_2016_200_Fig3_HTML.jpg

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