Redding Gregory J, Carter Edward R
Pulmonary Division, Seattle Children's Hospital, University of Washington School of Medicine , Seattle, WA , USA.
Pulmonary and Sleep Medicine, Banner Children's Specialists, Banner Medical Group , Phoenix, AZ , USA.
Front Pediatr. 2017 Feb 27;5:30. doi: 10.3389/fped.2017.00030. eCollection 2017.
The most common clinical suppurative lung conditions in children are empyema, lung abscess, and bronchiectasis, and to a less often necrotizing pneumonia. Until recently, bronchiectasis was the most common form of persistent suppurative lung disease in children. Protracted bacterial bronchitis is a newly described chronic suppurative condition in children, which is less persistent but more common than bronchiectasis (1). In addition, the term "chronic suppurative lung disease" has been used recently to describe the clinical features of bronchiectasis when the radiographic features needed to make a diagnosis of bronchiectasis are absent. Webster's New College Dictionary defines suppuration as the process of forming and/or discharging pus. Pus is a body fluid resulting from intense inflammation in response to infection that leads to neutrophil influx and apoptosis, microbial clearance, and often necrosis of nearby tissue. Pus is primarily composed of white blood cell debris.
儿童最常见的临床化脓性肺部疾病是脓胸、肺脓肿和支气管扩张，坏死性肺炎相对少见。直到最近，支气管扩张仍是儿童持续性化脓性肺部疾病最常见的形式。迁延性细菌性支气管炎是一种新描述的儿童慢性化脓性疾病，其持续性较支气管扩张轻，但更为常见（1）。此外，当缺乏诊断支气管扩张所需的影像学特征时，“慢性化脓性肺部疾病”一词最近被用于描述支气管扩张的临床特征。《韦氏新大学词典》将化脓定义为形成和/或排出脓液的过程。脓液是因感染引发强烈炎症而产生的体液，导致中性粒细胞流入和凋亡、微生物清除，且附近组织常发生坏死。脓液主要由白细胞碎片组成。
