Suppr超能文献

在初级保健中识别记忆障碍和早期痴呆症。

Identifying memory impairment and early dementia in primary care.

作者信息

Grober Ellen, Wakefield Dorothy, Ehrlich Amy R, Mabie Peter, Lipton Richard B

机构信息

Department of Neurology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA.

Center on Aging, UConn Health, Farmington, CT, USA.

出版信息

Alzheimers Dement (Amst). 2017 Feb 24;6:188-195. doi: 10.1016/j.dadm.2017.01.006. eCollection 2017.

Abstract

INTRODUCTION

This study examined the operating characteristics of two-stage case finding to identify memory impairment and very mild dementia.

METHODS

Primary care patients underwent two-stage testing and a subsequent diagnostic assessment to assess outcomes. Patients who screen positive for subjective cognitive decline on the Informant Questionnaire on Cognitive Decline in the Elderly undergo memory testing with the Free and Cued Selective Reminding Test with Immediate Recall. Outcomes were determined without access to these data. A split-half design with discovery and confirmatory samples was used.

RESULTS

One hundred seventeen of 563 (21%) patients had dementia and 68 (12%) had memory impairment but not dementia. Operating characteristics were similar in the discovery and confirmatory samples. In the pooled sample, combined, patients with memory impairment or dementia were identified with good sensitivity (72%) and high specificity (90%). Differences in ethnicity, educational level, or age (≤75, >75) did not affect classification accuracy.

DISCUSSION

Two-stage screening facilitates the efficient identification of older adults with memory impairment or dementia.

摘要

引言

本研究考察了两阶段病例筛查法用于识别记忆障碍和极轻度痴呆的操作特性。

方法

初级保健患者接受两阶段测试及后续诊断评估以评定结果。在《老年人认知功能下降知情者问卷》中筛查出主观认知功能下降呈阳性的患者,采用带即时回忆的自由和线索选择性回忆测验进行记忆测试。在无法获取这些数据的情况下确定结果。采用了包含发现样本和验证样本的对半设计。

结果

563名患者中有117名(21%)患有痴呆,68名(12%)有记忆障碍但未患痴呆。发现样本和验证样本的操作特性相似。在合并样本中,记忆障碍或痴呆患者的综合识别具有良好的敏感性(72%)和较高的特异性(90%)。种族、教育水平或年龄(≤75岁、>75岁)的差异不影响分类准确性。

讨论

两阶段筛查有助于高效识别有记忆障碍或痴呆的老年人。

相似文献

1
Identifying memory impairment and early dementia in primary care.在初级保健中识别记忆障碍和早期痴呆症。
Alzheimers Dement (Amst). 2017 Feb 24;6:188-195. doi: 10.1016/j.dadm.2017.01.006. eCollection 2017.
2
3
Two-stage screening for early dementia in primary care.基层医疗中早期痴呆的两阶段筛查。
J Clin Exp Neuropsychol. 2016 Nov;38(9):1038-49. doi: 10.1080/13803395.2016.1187117. Epub 2016 Jun 7.
4
5

引用本文的文献

本文引用的文献

3
Two-stage screening for early dementia in primary care.基层医疗中早期痴呆的两阶段筛查。
J Clin Exp Neuropsychol. 2016 Nov;38(9):1038-49. doi: 10.1080/13803395.2016.1187117. Epub 2016 Jun 7.
4
Rates of formal diagnosis of dementia in primary care: The effect of screening.初级保健中痴呆症的正式诊断率:筛查的影响。
Alzheimers Dement (Amst). 2015 Mar 29;1(1):87-93. doi: 10.1016/j.dadm.2014.11.007. eCollection 2015 Mar.
10
Screening older Latinos for dementia in the primary care setting.在初级保健机构中对老年拉丁裔进行痴呆症筛查。
J Int Neuropsychol Soc. 2014 Sep;20(8):848-55. doi: 10.1017/S1355617714000708. Epub 2014 Aug 14.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验