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1型糖尿病患者为什么要定期锻炼?

Why should people with type 1 diabetes exercise regularly?

作者信息

Codella Roberto, Terruzzi Ileana, Luzi Livio

机构信息

Department of Biomedical Sciences for Health, University of Milan, Via F.lli Cervi 93, Segrate, 20090, Milan, Italy.

Diabetes Research Institute, Metabolism, Nutrigenomics and Cellular Differentiation Unit, San Raffaele Scientific Institute, Milan, Italy.

出版信息

Acta Diabetol. 2017 Jul;54(7):615-630. doi: 10.1007/s00592-017-0978-x. Epub 2017 Mar 14.

Abstract

Plethoric evidence reminds of the protective effects of exercise against a number of health risks, across all ages, in the general population. The benefits of exercise for individuals with type 2 diabetes are indisputable. An in-depth understanding of energy metabolism has reasonably entailed exercise as a cornerstone in the lifestyle of almost all subjects with type 1 diabetes. Nevertheless, individuals with type 1 diabetes often fail in accomplishing exercise guidelines and they are less active than their peer without diabetes. Two major obstacles are feared by people with type 1 diabetes who wish to exercise regularly: management of blood glucose control and hypoglycemia. Nowadays, strategies, including glucose monitoring technology and insulin pump therapy, have significantly contributed to the participation in regular physical activity, and even in competitive sports, for people with type 1 diabetes. Novel modalities of training, like different intensity, interspersed exercise, are as well promising. The beneficial potential of exercise in type 1 diabetes is multi-faceted, and it has to be fully exploited because it goes beyond the insulin-mimetic action, possibly through immunomodulation.

摘要

大量证据表明,运动对普通人群各年龄段的多种健康风险具有保护作用。运动对2型糖尿病患者的益处是无可争议的。对能量代谢的深入理解合理地使运动成为几乎所有1型糖尿病患者生活方式的基石。然而,1型糖尿病患者往往无法完成运动指南,且他们比无糖尿病的同龄人活动量更少。希望定期运动的1型糖尿病患者担心两个主要障碍:血糖控制管理和低血糖。如今,包括血糖监测技术和胰岛素泵治疗在内的策略,对1型糖尿病患者参与定期体育活动乃至竞技运动做出了重大贡献。新型训练方式,如不同强度、穿插式运动,也很有前景。运动对1型糖尿病的有益潜力是多方面的,必须充分加以利用,因为其作用可能通过免疫调节,超越了胰岛素模拟作用。

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